---
res:
  bibo_abstract:
  - ATP released from neurons and astrocytes during neuronal activity or under pathophysiological
    circumstances is able to influence information flow in neuronal circuits by activation
    of ionotropic P2X and metabotropic P2Y receptors and subsequent modulation of
    cellular excitability, synaptic strength, and plasticity. In the present paper
    we review cellular and network effects of P2Y receptors in the brain. We show
    that P2Y receptors inhibit the release of neurotransmitters, modulate voltage-
    and ligand-gated ion channels, and differentially influence the induction of synaptic
    plasticity in the prefrontal cortex, hippocampus, and cerebellum. The findings
    discussed here may explain how P2Y1 receptor activation during brain injury, hypoxia,
    inflammation, schizophrenia, or Alzheimer's disease leads to an impairment of
    cognitive processes. Hence, it is suggested that the blockade of P2Y1 receptors
    may have therapeutic potential against cognitive disturbances in these states.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: José
      foaf_name: Guzmán, José
      foaf_surname: Guzmán
      foaf_workInfoHomepage: http://www.librecat.org/personId=30CC5506-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-2209-5242
  - foaf_Person:
      foaf_givenName: Zoltan
      foaf_name: Gerevich, Zoltan
      foaf_surname: Gerevich
  bibo_doi: 10.1155/2016/1207393
  bibo_volume: 2016
  dct_date: 2016^xs_gYear
  dct_identifier:
  - UT:000374056200001
  dct_language: eng
  dct_publisher: Hindawi Publishing Corporation@
  dct_title: 'P2Y receptors in synaptic transmission and plasticity: Therapeutic potential
    in cognitive dysfunction@'
...