conference paper published yes Nikola Beneš author Luboš Brim author Samuel Pastva author 07c5ea74-f61c-11ec-a664-aa7c5d957b2b0000-0003-1993-0331 David Šafránek author Eva Šmijáková author ToHe department CMSB: Computational Methods in Systems Biology IST-BRIDGE: International postdoctoral program project Partially specified Boolean networks (PSBNs) represent a promising framework for the qualitative modelling of biological systems in which the logic of interactions is not completely known. Phenotype control aims to stabilise the network in states exhibiting specific traits. In this paper, we define the phenotype control problem in the context of asynchronous PSBNs and propose a novel semi-symbolic algorithm for solving this problem with permanent variable perturbations. https://research-explorer.ista.ac.at/download/14411/14997/cmsb2023.pdf application/pdfno Springer Nature2023Luxembourg City, Luxembourg eng 0302-9743 1611-3349 9783031426964 00115628060000210.1007/978-3-031-42697-1_2 1413718-35 N. Beneš, L. Brim, S. Pastva, D. Šafránek, E. Šmijáková, in:, 21st International Conference on Computational Methods in Systems Biology, Springer Nature, 2023, pp. 18–35. Beneš, Nikola, Luboš Brim, Samuel Pastva, David Šafránek, and Eva Šmijáková. “Phenotype Control of Partially Specified Boolean Networks.” In <i>21st International Conference on Computational Methods in Systems Biology</i>, 14137:18–35. Springer Nature, 2023. <a href="https://doi.org/10.1007/978-3-031-42697-1_2">https://doi.org/10.1007/978-3-031-42697-1_2</a>. Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. 2023. Phenotype control of partially specified boolean networks. 21st International Conference on Computational Methods in Systems Biology. CMSB: Computational Methods in Systems Biology, LNBI, vol. 14137, 18–35. Beneš, N., Brim, L., Pastva, S., Šafránek, D., &#38; Šmijáková, E. (2023). Phenotype control of partially specified boolean networks. In <i>21st International Conference on Computational Methods in Systems Biology</i> (Vol. 14137, pp. 18–35). Luxembourg City, Luxembourg: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-42697-1_2">https://doi.org/10.1007/978-3-031-42697-1_2</a> Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. Phenotype control of partially specified boolean networks. In: <i>21st International Conference on Computational Methods in Systems Biology</i>. Vol 14137. Springer Nature; 2023:18-35. doi:<a href="https://doi.org/10.1007/978-3-031-42697-1_2">10.1007/978-3-031-42697-1_2</a> Beneš, Nikola, et al. “Phenotype Control of Partially Specified Boolean Networks.” <i>21st International Conference on Computational Methods in Systems Biology</i>, vol. 14137, Springer Nature, 2023, pp. 18–35, doi:<a href="https://doi.org/10.1007/978-3-031-42697-1_2">10.1007/978-3-031-42697-1_2</a>. N. Beneš, L. Brim, S. Pastva, D. Šafránek, and E. Šmijáková, “Phenotype control of partially specified boolean networks,” in <i>21st International Conference on Computational Methods in Systems Biology</i>, Luxembourg City, Luxembourg, 2023, vol. 14137, pp. 18–35. 144112023-10-08T22:01:18Z2025-09-09T14:25:46Z