---
OA_place: publisher
OA_type: hybrid
_id: '14463'
abstract:
- lang: eng
  text: Inversions are thought to play a key role in adaptation and speciation, suppressing
    recombination between diverging populations. Genes influencing adaptive traits
    cluster in inversions, and changes in inversion frequencies are associated with
    environmental differences. However, in many organisms, it is unclear if inversions
    are geographically and taxonomically widespread. The intertidal snail, Littorina
    saxatilis, is one such example. Strong associations between putative polymorphic
    inversions and phenotypic differences have been demonstrated between two ecotypes
    of L. saxatilis in Sweden and inferred elsewhere, but no direct evidence for inversion
    polymorphism currently exists across the species range. Using whole genome data
    from 107 snails, most inversion polymorphisms were found to be widespread across
    the species range. The frequencies of some inversion arrangements were significantly
    different among ecotypes, suggesting a parallel adaptive role. Many inversions
    were also polymorphic in the sister species, L. arcana, hinting at an ancient
    origin.
acknowledgement: We would like to thank members of the Littorina team for their advice
  and feedback during this project. In particular, we thank Alan Le Moan, who inspired
  us to look at heterozygosity differences to identify inversions, and Katherine Hearn
  for helping with the PCA scripts. We thank Edinburgh Genomics for library preparation
  and sequencing. Sample collections, sequencing and data preparation were supported
  by the European Research Council (ERC-2015-AdG-693030- BARRIERS) and the Natural
  Environment Research Council (NE/P001610/1). The analysis was supported by the Swedish
  Research Council (vetenskaprådet; 2018-03695_VR) and the Portuguese Foundation for
  Science and Technology (Fundación para a Ciência e Tecnologia) through a research
  project (PTDC/BIA-EVL/1614/2021) and CEEC contract (2020.00275.CEECIND).
article_number: e17160
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: James
  full_name: Reeve, James
  last_name: Reeve
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
- first_name: Eva L.
  full_name: Koch, Eva L.
  last_name: Koch
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
citation:
  ama: Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. Chromosomal inversion polymorphisms
    are widespread across the species ranges of rough periwinkles (Littorina saxatilis
    and L. arcana). <i>Molecular Ecology</i>. 2024;33(24). doi:<a href="https://doi.org/10.1111/mec.17160">10.1111/mec.17160</a>
  apa: Reeve, J., Butlin, R. K., Koch, E. L., Stankowski, S., &#38; Faria, R. (2024).
    Chromosomal inversion polymorphisms are widespread across the species ranges of
    rough periwinkles (Littorina saxatilis and L. arcana). <i>Molecular Ecology</i>.
    Wiley. <a href="https://doi.org/10.1111/mec.17160">https://doi.org/10.1111/mec.17160</a>
  chicago: Reeve, James, Roger K. Butlin, Eva L. Koch, Sean Stankowski, and Rui Faria.
    “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges
    of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” <i>Molecular Ecology</i>.
    Wiley, 2024. <a href="https://doi.org/10.1111/mec.17160">https://doi.org/10.1111/mec.17160</a>.
  ieee: J. Reeve, R. K. Butlin, E. L. Koch, S. Stankowski, and R. Faria, “Chromosomal
    inversion polymorphisms are widespread across the species ranges of rough periwinkles
    (Littorina saxatilis and L. arcana),” <i>Molecular Ecology</i>, vol. 33, no. 24.
    Wiley, 2024.
  ista: Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. 2024. Chromosomal inversion
    polymorphisms are widespread across the species ranges of rough periwinkles (Littorina
    saxatilis and L. arcana). Molecular Ecology. 33(24), e17160.
  mla: Reeve, James, et al. “Chromosomal Inversion Polymorphisms Are Widespread across
    the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).”
    <i>Molecular Ecology</i>, vol. 33, no. 24, e17160, Wiley, 2024, doi:<a href="https://doi.org/10.1111/mec.17160">10.1111/mec.17160</a>.
  short: J. Reeve, R.K. Butlin, E.L. Koch, S. Stankowski, R. Faria, Molecular Ecology
    33 (2024).
date_created: 2023-10-29T23:01:17Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-01-09T07:53:18Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/mec.17160
external_id:
  isi:
  - '001085119000001'
  pmid:
  - '37843465'
file:
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fulldoi: https://doi.org/10.1111/mec.17160
has_accepted_license: '1'
intvolume: '        33'
isi: 1
issue: '24'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Molecular Ecology
publication_identifier:
  eissn:
  - 1365-294X
  issn:
  - 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromosomal inversion polymorphisms are widespread across the species ranges
  of rough periwinkles (Littorina saxatilis and L. arcana)
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
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...