Transverse fluctuations control the assembly of semiflexible filaments Sorichetti, Valerio ; https://orcid.org/0000-0002-9645-6576 Lenz, Martin The kinetics of the assembly of semiflexible filaments through end-to-end annealing is key to the structure of the cytoskeleton, but is not understood. We analyze this problem through scaling theory and simulations, and uncover a regime where filaments’ ends find each other through bending fluctuations without the need for the whole filament to diffuse. This results in a very substantial speedup of assembly in physiological regimes, and could help with understanding the dynamics of actin and intermediate filaments in biological processes such as wound healing and cell division. American Physical Society 2023 info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_2df8fbb1 https://research-explorer.ista.ac.at/record/14655 Sorichetti V, Lenz M. Transverse fluctuations control the assembly of semiflexible filaments. <i>Physical Review Letters</i>. 2023;131(22). doi:<a href="https://doi.org/10.1103/PhysRevLett.131.228401">10.1103/PhysRevLett.131.228401</a> eng info:eu-repo/semantics/altIdentifier/doi/10.1103/PhysRevLett.131.228401 info:eu-repo/semantics/altIdentifier/issn/0031-9007 info:eu-repo/semantics/altIdentifier/e-issn/1079-7114 info:eu-repo/semantics/altIdentifier/wos/001163810200008 info:eu-repo/semantics/altIdentifier/arxiv/2303.03088 info:eu-repo/semantics/altIdentifier/pmid/38101392 info:eu-repo/semantics/openAccess