LIONESS enables 4D nanoscale reconstruction of living brain tissue Danzl, Johann G ; https://orcid.org/0000-0001-8559-3973 Velicky, Philipp ; https://orcid.org/0000-0002-2340-7431 Cell Biology Molecular Biology Biochemistry Biotechnology We developed LIONESS, a technology that leverages improvements to optical super-resolution microscopy and prior information on sample structure via machine learning to overcome the limitations (in 3D-resolution, signal-to-noise ratio and light exposure) of optical microscopy of living biological specimens. LIONESS enables dense reconstruction of living brain tissue and morphodynamics visualization at the nanoscale. Springer Nature 2023 info:eu-repo/semantics/article doc-type:Article Article http://purl.org/coar/resource_type/c_6501 https://research-explorer.ista.ac.at/record/14770 Danzl JG, Velicky P. LIONESS enables 4D nanoscale reconstruction of living brain tissue. <i>Nature Methods</i>. 2023;20(8):1141-1142. doi:<a href="https://doi.org/10.1038/s41592-023-01937-5">10.1038/s41592-023-01937-5</a> eng info:eu-repo/semantics/altIdentifier/doi/10.1038/s41592-023-01937-5 info:eu-repo/semantics/altIdentifier/issn/1548-7091 info:eu-repo/semantics/altIdentifier/e-issn/1548-7105 info:eu-repo/semantics/altIdentifier/wos/001025621500002 info:eu-repo/semantics/closedAccess