---
res:
  bibo_abstract:
  - The next steps of deep space exploration are manned missions to Moon and Mars.
    For safe space missions for crew members, it is important to understand the impact
    of space flight on the immune system. We studied the effects of 21 days dry immersion
    (DI) exposure on the transcriptomes of T cells isolated from blood samples of
    eight healthy volunteers. Samples were collected 7 days before DI, at day 7, 14,
    and 21 during DI, and 7 days after DI. RNA sequencing of CD3+T cells revealed
    transcriptional alterations across all time points, with most changes occurring
    14 days after DI exposure. At day 21, T cells showed evidence of adaptation with
    a transcriptional profile resembling that of 7 days before DI. At 7 days after
    DI, T cells again changed their transcriptional profile. These data suggest that
    T cells adapt by rewiring their transcriptomes in response to simulated weightlessness
    and that remodeling cues persist when reexposed to normal gravity.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Carlos J.
      foaf_name: Gallardo-Dodd, Carlos J.
      foaf_surname: Gallardo-Dodd
  - foaf_Person:
      foaf_givenName: Christian
      foaf_name: Oertlin, Christian
      foaf_surname: Oertlin
  - foaf_Person:
      foaf_givenName: Julien
      foaf_name: Record, Julien
      foaf_surname: Record
  - foaf_Person:
      foaf_givenName: Rômulo G.
      foaf_name: Galvani, Rômulo G.
      foaf_surname: Galvani
  - foaf_Person:
      foaf_givenName: Christian
      foaf_name: Sommerauer, Christian
      foaf_surname: Sommerauer
  - foaf_Person:
      foaf_givenName: Nikolai V.
      foaf_name: Kuznetsov, Nikolai V.
      foaf_surname: Kuznetsov
  - foaf_Person:
      foaf_givenName: Evangelos
      foaf_name: Doukoumopoulos, Evangelos
      foaf_surname: Doukoumopoulos
  - foaf_Person:
      foaf_givenName: Liaqat
      foaf_name: Ali, Liaqat
      foaf_surname: Ali
  - foaf_Person:
      foaf_givenName: Mariana M. S.
      foaf_name: Oliveira, Mariana M. S.
      foaf_surname: Oliveira
  - foaf_Person:
      foaf_givenName: Christina
      foaf_name: Seitz, Christina
      foaf_surname: Seitz
  - foaf_Person:
      foaf_givenName: Mathias
      foaf_name: Percipalle, Mathias
      foaf_surname: Percipalle
      foaf_workInfoHomepage: http://www.librecat.org/personId=4986e21c-eb97-11eb-a6c2-a4ef0b629971
  - foaf_Person:
      foaf_givenName: Tijana
      foaf_name: Nikić, Tijana
      foaf_surname: Nikić
  - foaf_Person:
      foaf_givenName: Anastasia A.
      foaf_name: Sadova, Anastasia A.
      foaf_surname: Sadova
  - foaf_Person:
      foaf_givenName: Sofia M.
      foaf_name: Shulgina, Sofia M.
      foaf_surname: Shulgina
  - foaf_Person:
      foaf_givenName: Vjacheslav A.
      foaf_name: Shmarov, Vjacheslav A.
      foaf_surname: Shmarov
  - foaf_Person:
      foaf_givenName: Olga V.
      foaf_name: Kutko, Olga V.
      foaf_surname: Kutko
  - foaf_Person:
      foaf_givenName: Daria D.
      foaf_name: Vlasova, Daria D.
      foaf_surname: Vlasova
  - foaf_Person:
      foaf_givenName: Kseniya D.
      foaf_name: Orlova, Kseniya D.
      foaf_surname: Orlova
  - foaf_Person:
      foaf_givenName: Marina P.
      foaf_name: Rykova, Marina P.
      foaf_surname: Rykova
  - foaf_Person:
      foaf_givenName: John
      foaf_name: Andersson, John
      foaf_surname: Andersson
  - foaf_Person:
      foaf_givenName: Piergiorgio
      foaf_name: Percipalle, Piergiorgio
      foaf_surname: Percipalle
  - foaf_Person:
      foaf_givenName: Claudia
      foaf_name: Kutter, Claudia
      foaf_surname: Kutter
  - foaf_Person:
      foaf_givenName: Sergey A.
      foaf_name: Ponomarev, Sergey A.
      foaf_surname: Ponomarev
  - foaf_Person:
      foaf_givenName: Lisa S.
      foaf_name: Westerberg, Lisa S.
      foaf_surname: Westerberg
  bibo_doi: 10.1126/sciadv.adg1610
  bibo_issue: '34'
  bibo_volume: 9
  dct_date: 2023^xs_gYear
  dct_identifier:
  - UT:001054596800007
  dct_isPartOf:
  - http://id.crossref.org/issn/2375-2548
  dct_language: eng
  dct_publisher: American Association for the Advancement of Science@
  dct_subject:
  - Multidisciplinary
  dct_title: Exposure of volunteers to microgravity by dry immersion bed over 21 days
    results in gene expression changes and adaptation of T cells@
  fabio_hasPubmedId: '37624890'
...