---
_id: '1487'
abstract:
- lang: eng
text: Rhythms with time scales of multiple cycles per second permeate the mammalian
brain, yet neuroscientists are not certain of their functional roles. One leading
idea is that coherent oscillation between two brain regions facilitates the exchange
of information between them. In rats, the hippocampus and the vibrissal sensorimotor
system both are characterized by rhythmic oscillation in the theta range, 5–12
Hz. Previous work has been divided as to whether the two rhythms are independent
or coherent. To resolve this question, we acquired three measures from rats—whisker
motion, hippocampal local field potential (LFP), and barrel cortex unit firing—during
a whisker-mediated texture discrimination task and during control conditions (not
engaged in a whisker-mediated memory task). Compared to control conditions, the
theta band of hippocampal LFP showed a marked increase in power as the rats approached
and then palpated the texture. Phase synchronization between whisking and hippocampal
LFP increased by almost 50% during approach and texture palpation. In addition,
a greater proportion of barrel cortex neurons showed firing that was phase-locked
to hippocampal theta while rats were engaged in the discrimination task. Consistent
with a behavioral consequence of phase synchronization, the rats identified the
texture more rapidly and with lower error likelihood on trials in which there
was an increase in theta-whisking coherence at the moment of texture palpation.
These results suggest that coherence between the whisking rhythm, barrel cortex
firing, and hippocampal LFP is augmented selectively during epochs in which the
rat collects sensory information and that such coherence enhances the efficiency
of integration of stimulus information into memory and decision-making centers.
acknowledgement: We thank Eric Maris, Demian Battaglia, and Rodrigo Quian Quiroga
for useful discussions. We are grateful to Fabrizio Manzino and Marco Gigante for
construction of the behavioral apparatus, Igor Perkon for developing custom whisker
tracking software and to Francesca Pulecchi for animal care and histological processing.
article_number: e1002384
author:
- first_name: Natalia
full_name: Grion, Natalia
last_name: Grion
- first_name: Athena
full_name: Akrami, Athena
last_name: Akrami
- first_name: Yangfang
full_name: Zuo, Yangfang
last_name: Zuo
- first_name: Federico
full_name: Stella, Federico
id: 39AF1E74-F248-11E8-B48F-1D18A9856A87
last_name: Stella
orcid: 0000-0001-9439-3148
- first_name: Mathew
full_name: Diamond, Mathew
last_name: Diamond
citation:
ama: Grion N, Akrami A, Zuo Y, Stella F, Diamond M. Coherence between rat sensorimotor
system and hippocampus is enhanced during tactile discrimination. PLoS Biology.
2016;14(2). doi:10.1371/journal.pbio.1002384
apa: Grion, N., Akrami, A., Zuo, Y., Stella, F., & Diamond, M. (2016). Coherence
between rat sensorimotor system and hippocampus is enhanced during tactile discrimination.
PLoS Biology. Public Library of Science. https://doi.org/10.1371/journal.pbio.1002384
chicago: Grion, Natalia, Athena Akrami, Yangfang Zuo, Federico Stella, and Mathew
Diamond. “Coherence between Rat Sensorimotor System and Hippocampus Is Enhanced
during Tactile Discrimination.” PLoS Biology. Public Library of Science,
2016. https://doi.org/10.1371/journal.pbio.1002384.
ieee: N. Grion, A. Akrami, Y. Zuo, F. Stella, and M. Diamond, “Coherence between
rat sensorimotor system and hippocampus is enhanced during tactile discrimination,”
PLoS Biology, vol. 14, no. 2. Public Library of Science, 2016.
ista: Grion N, Akrami A, Zuo Y, Stella F, Diamond M. 2016. Coherence between rat
sensorimotor system and hippocampus is enhanced during tactile discrimination.
PLoS Biology. 14(2), e1002384.
mla: Grion, Natalia, et al. “Coherence between Rat Sensorimotor System and Hippocampus
Is Enhanced during Tactile Discrimination.” PLoS Biology, vol. 14, no.
2, e1002384, Public Library of Science, 2016, doi:10.1371/journal.pbio.1002384.
short: N. Grion, A. Akrami, Y. Zuo, F. Stella, M. Diamond, PLoS Biology 14 (2016).
date_created: 2018-12-11T11:52:18Z
date_published: 2016-02-18T00:00:00Z
date_updated: 2021-01-12T06:51:05Z
day: '18'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.1371/journal.pbio.1002384
file:
- access_level: open_access
checksum: 3a5ce0d4e4e36bd6ceb4be761f85644a
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:11Z
date_updated: 2020-07-14T12:44:57Z
file_id: '5129'
file_name: IST-2016-518-v1+1_journal.pbio.1002384.PDF
file_size: 2879899
relation: main_file
file_date_updated: 2020-07-14T12:44:57Z
has_accepted_license: '1'
intvolume: ' 14'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5700'
pubrep_id: '518'
quality_controlled: '1'
scopus_import: 1
status: public
title: Coherence between rat sensorimotor system and hippocampus is enhanced during
tactile discrimination
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2016'
...