---
res:
  bibo_abstract:
  - Cell movement has essential functions in development, immunity, and cancer. Various
    cell migration patterns have been reported, but no general rule has emerged so
    far. Here, we show on the basis of experimental data in vitro and in vivo that
    cell persistence, which quantifies the straightness of trajectories, is robustly
    coupled to cell migration speed. We suggest that this universal coupling constitutes
    a generic law of cell migration, which originates in the advection of polarity
    cues by an actin cytoskeleton undergoing flows at the cellular scale. Our analysis
    relies on a theoretical model that we validate by measuring the persistence of
    cells upon modulation of actin flow speeds and upon optogenetic manipulation of
    the binding of an actin regulator to actin filaments. Beyond the quantitative
    prediction of the coupling, the model yields a generic phase diagram of cellular
    trajectories, which recapitulates the full range of observed migration patterns.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Paolo
      foaf_name: Maiuri, Paolo
      foaf_surname: Maiuri
  - foaf_Person:
      foaf_givenName: Jean
      foaf_name: Rupprecht, Jean
      foaf_surname: Rupprecht
  - foaf_Person:
      foaf_givenName: Stefan
      foaf_name: Wieser, Stefan
      foaf_surname: Wieser
      foaf_workInfoHomepage: http://www.librecat.org/personId=355AA5A0-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-2670-2217
  - foaf_Person:
      foaf_givenName: Verena
      foaf_name: Ruprecht, Verena
      foaf_surname: Ruprecht
      foaf_workInfoHomepage: http://www.librecat.org/personId=4D71A03A-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-4088-8633
  - foaf_Person:
      foaf_givenName: Olivier
      foaf_name: Bénichou, Olivier
      foaf_surname: Bénichou
  - foaf_Person:
      foaf_givenName: Nicolas
      foaf_name: Carpi, Nicolas
      foaf_surname: Carpi
  - foaf_Person:
      foaf_givenName: Mathieu
      foaf_name: Coppey, Mathieu
      foaf_surname: Coppey
  - foaf_Person:
      foaf_givenName: Simon
      foaf_name: De Beco, Simon
      foaf_surname: De Beco
  - foaf_Person:
      foaf_givenName: Nir
      foaf_name: Gov, Nir
      foaf_surname: Gov
  - foaf_Person:
      foaf_givenName: Carl-Philipp J
      foaf_name: Heisenberg, Carl-Philipp J
      foaf_surname: Heisenberg
      foaf_workInfoHomepage: http://www.librecat.org/personId=39427864-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-0912-4566
  - foaf_Person:
      foaf_givenName: Carolina
      foaf_name: Lage Crespo, Carolina
      foaf_surname: Lage Crespo
  - foaf_Person:
      foaf_givenName: Franziska
      foaf_name: Lautenschlaeger, Franziska
      foaf_surname: Lautenschlaeger
  - foaf_Person:
      foaf_givenName: Maël
      foaf_name: Le Berre, Maël
      foaf_surname: Le Berre
  - foaf_Person:
      foaf_givenName: Ana
      foaf_name: Lennon Duménil, Ana
      foaf_surname: Lennon Duménil
  - foaf_Person:
      foaf_givenName: Matthew
      foaf_name: Raab, Matthew
      foaf_surname: Raab
  - foaf_Person:
      foaf_givenName: Hawa
      foaf_name: Thiam, Hawa
      foaf_surname: Thiam
  - foaf_Person:
      foaf_givenName: Matthieu
      foaf_name: Piel, Matthieu
      foaf_surname: Piel
  - foaf_Person:
      foaf_givenName: Michael K
      foaf_name: Sixt, Michael K
      foaf_surname: Sixt
      foaf_workInfoHomepage: http://www.librecat.org/personId=41E9FBEA-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-6620-9179
  - foaf_Person:
      foaf_givenName: Raphaël
      foaf_name: Voituriez, Raphaël
      foaf_surname: Voituriez
  bibo_doi: 10.1016/j.cell.2015.01.056
  bibo_issue: '2'
  bibo_volume: 161
  dct_date: 2015^xs_gYear
  dct_identifier:
  - UT:000352708300028
  dct_language: eng
  dct_publisher: Cell Press@
  dct_title: Actin flows mediate a universal coupling between cell speed and cell
    persistence@
...