---
_id: '1556'
abstract:
- lang: eng
  text: The elongator complex subunit 2 (ELP2) protein, one subunit of an evolutionarily
    conserved histone acetyltransferase complex, has been shown to participate in
    leaf patterning, plant immune and abiotic stress responses in Arabidopsis thaliana.
    Here, its role in root development was explored. Compared to the wild type, the
    elp2 mutant exhibited an accelerated differentiation of its root stem cells and
    cell division was more active in its quiescent centre (QC). The key transcription
    factors responsible for maintaining root stem cell and QC identity, such as AP2
    transcription factors PLT1 (PLETHORA1) and PLT2 (PLETHORA2), GRAS transcription
    factors such as SCR (SCARECROW) and SHR (SHORT ROOT) and WUSCHEL-RELATED HOMEOBOX5
    transcription factor WOX5, were all strongly down-regulated in the mutant. On
    the other hand, expression of the G2/M transition activator CYCB1 was substantially
    induced in elp2. The auxin efflux transporters PIN1 and PIN2 showed decreased
    protein levels and PIN1 also displayed mild polarity alterations in elp2, which
    resulted in a reduced auxin content in the root tip. Either the acetylation or
    methylation level of each of these genes differed between the mutant and the wild
    type, suggesting that the ELP2 regulation of root development involves the epigenetic
    modification of a range of transcription factors and other developmental regulators.
article_processing_charge: No
author:
- first_name: Yuebin
  full_name: Jia, Yuebin
  last_name: Jia
- first_name: Huiyu
  full_name: Tian, Huiyu
  last_name: Tian
- first_name: Hongjiang
  full_name: Li, Hongjiang
  id: 33CA54A6-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0001-5039-9660
- first_name: Qianqian
  full_name: Yu, Qianqian
  last_name: Yu
- first_name: Lei
  full_name: Wang, Lei
  last_name: Wang
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Zhaojun
  full_name: Ding, Zhaojun
  last_name: Ding
citation:
  ama: Jia Y, Tian H, Li H, et al. The Arabidopsis thaliana elongator complex subunit
    2 epigenetically affects root development. <i>Journal of Experimental Botany</i>.
    2015;66(15):4631-4642. doi:<a href="https://doi.org/10.1093/jxb/erv230">10.1093/jxb/erv230</a>
  apa: Jia, Y., Tian, H., Li, H., Yu, Q., Wang, L., Friml, J., &#38; Ding, Z. (2015).
    The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root
    development. <i>Journal of Experimental Botany</i>. Oxford University Press. <a
    href="https://doi.org/10.1093/jxb/erv230">https://doi.org/10.1093/jxb/erv230</a>
  chicago: Jia, Yuebin, Huiyu Tian, Hongjiang Li, Qianqian Yu, Lei Wang, Jiří Friml,
    and Zhaojun Ding. “The Arabidopsis Thaliana Elongator Complex Subunit 2 Epigenetically
    Affects Root Development.” <i>Journal of Experimental Botany</i>. Oxford University
    Press, 2015. <a href="https://doi.org/10.1093/jxb/erv230">https://doi.org/10.1093/jxb/erv230</a>.
  ieee: Y. Jia <i>et al.</i>, “The Arabidopsis thaliana elongator complex subunit
    2 epigenetically affects root development,” <i>Journal of Experimental Botany</i>,
    vol. 66, no. 15. Oxford University Press, pp. 4631–4642, 2015.
  ista: Jia Y, Tian H, Li H, Yu Q, Wang L, Friml J, Ding Z. 2015. The Arabidopsis
    thaliana elongator complex subunit 2 epigenetically affects root development.
    Journal of Experimental Botany. 66(15), 4631–4642.
  mla: Jia, Yuebin, et al. “The Arabidopsis Thaliana Elongator Complex Subunit 2 Epigenetically
    Affects Root Development.” <i>Journal of Experimental Botany</i>, vol. 66, no.
    15, Oxford University Press, 2015, pp. 4631–42, doi:<a href="https://doi.org/10.1093/jxb/erv230">10.1093/jxb/erv230</a>.
  short: Y. Jia, H. Tian, H. Li, Q. Yu, L. Wang, J. Friml, Z. Ding, Journal of Experimental
    Botany 66 (2015) 4631–4642.
date_created: 2018-12-11T11:52:42Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2025-09-23T13:42:27Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1093/jxb/erv230
external_id:
  isi:
  - '000359687400017'
file:
- access_level: open_access
  checksum: 257919be0ce3d306185d3891ad7acf39
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:02Z
  date_updated: 2020-07-14T12:45:02Z
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  file_name: IST-2016-480-v1+1_J._Exp._Bot.-2015-Jia-4631-42.pdf
  file_size: 7753043
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file_date_updated: 2020-07-14T12:45:02Z
fulldoi: https://doi.org/10.1093/jxb/erv230
has_accepted_license: '1'
intvolume: '        66'
isi: 1
issue: '15'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 4631 - 4642
publication: Journal of Experimental Botany
publication_status: published
publisher: Oxford University Press
publist_id: '5615'
pubrep_id: '480'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects
  root development
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 66
year: '2015'
...