---
_id: '1574'
abstract:
- lang: eng
  text: Multiple plant developmental processes, such as lateral root development,
    depend on auxin distribution patterns that are in part generated by the PIN-formed
    family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7
    (ARF7) and the ARF7-regulated FOUR LIPS/MYB124 (FLP) transcription factors jointly
    form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription
    in planta to steer the early steps of lateral root formation. This regulatory
    mechanism might endow the PIN3 circuitry with a temporal 'memory' of auxin stimuli,
    potentially maintaining and enhancing the robustness of the auxin flux directionality
    during lateral root development. The cooperative action between canonical auxin
    signalling and other transcription factors might constitute a general mechanism
    by which transcriptional auxin-sensitivity can be regulated at a tissue-specific
    level.
acknowledgement: 'of the European Research Council (project ERC-2011-StG-20101109-PSDP)
  (to J.F.), a FEBS long-term fellowship (to P.M.) '
article_number: '8821'
article_processing_charge: No
author:
- first_name: Qian
  full_name: Chen, Qian
  last_name: Chen
- first_name: Yang
  full_name: Liu, Yang
  last_name: Liu
- first_name: Steven
  full_name: Maere, Steven
  last_name: Maere
- first_name: Eunkyoung
  full_name: Lee, Eunkyoung
  last_name: Lee
- first_name: Gert
  full_name: Van Isterdael, Gert
  last_name: Van Isterdael
- first_name: Zidian
  full_name: Xie, Zidian
  last_name: Xie
- first_name: Wei
  full_name: Xuan, Wei
  last_name: Xuan
- first_name: Jessica
  full_name: Lucas, Jessica
  last_name: Lucas
- first_name: Valya
  full_name: Vassileva, Valya
  last_name: Vassileva
- first_name: Saeko
  full_name: Kitakura, Saeko
  last_name: Kitakura
- first_name: Peter
  full_name: Marhavy, Peter
  id: 3F45B078-F248-11E8-B48F-1D18A9856A87
  last_name: Marhavy
  orcid: 0000-0001-5227-5741
- first_name: Krzysztof T
  full_name: Wabnik, Krzysztof T
  id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
  last_name: Wabnik
  orcid: 0000-0001-7263-0560
- first_name: Niko
  full_name: Geldner, Niko
  last_name: Geldner
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Jie
  full_name: Le, Jie
  last_name: Le
- first_name: Hidehiro
  full_name: Fukaki, Hidehiro
  last_name: Fukaki
- first_name: Erich
  full_name: Grotewold, Erich
  last_name: Grotewold
- first_name: Chuanyou
  full_name: Li, Chuanyou
  last_name: Li
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Fred
  full_name: Sack, Fred
  last_name: Sack
- first_name: Tom
  full_name: Beeckman, Tom
  last_name: Beeckman
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
citation:
  ama: Chen Q, Liu Y, Maere S, et al. A coherent transcriptional feed-forward motif
    model for mediating auxin-sensitive PIN3 expression during lateral root development.
    <i>Nature Communications</i>. 2015;6. doi:<a href="https://doi.org/10.1038/ncomms9821">10.1038/ncomms9821</a>
  apa: Chen, Q., Liu, Y., Maere, S., Lee, E., Van Isterdael, G., Xie, Z., … Vanneste,
    S. (2015). A coherent transcriptional feed-forward motif model for mediating auxin-sensitive
    PIN3 expression during lateral root development. <i>Nature Communications</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/ncomms9821">https://doi.org/10.1038/ncomms9821</a>
  chicago: Chen, Qian, Yang Liu, Steven Maere, Eunkyoung Lee, Gert Van Isterdael,
    Zidian Xie, Wei Xuan, et al. “A Coherent Transcriptional Feed-Forward Motif Model
    for Mediating Auxin-Sensitive PIN3 Expression during Lateral Root Development.”
    <i>Nature Communications</i>. Nature Publishing Group, 2015. <a href="https://doi.org/10.1038/ncomms9821">https://doi.org/10.1038/ncomms9821</a>.
  ieee: Q. Chen <i>et al.</i>, “A coherent transcriptional feed-forward motif model
    for mediating auxin-sensitive PIN3 expression during lateral root development,”
    <i>Nature Communications</i>, vol. 6. Nature Publishing Group, 2015.
  ista: Chen Q, Liu Y, Maere S, Lee E, Van Isterdael G, Xie Z, Xuan W, Lucas J, Vassileva
    V, Kitakura S, Marhavý P, Wabnik KT, Geldner N, Benková E, Le J, Fukaki H, Grotewold
    E, Li C, Friml J, Sack F, Beeckman T, Vanneste S. 2015. A coherent transcriptional
    feed-forward motif model for mediating auxin-sensitive PIN3 expression during
    lateral root development. Nature Communications. 6, 8821.
  mla: Chen, Qian, et al. “A Coherent Transcriptional Feed-Forward Motif Model for
    Mediating Auxin-Sensitive PIN3 Expression during Lateral Root Development.” <i>Nature
    Communications</i>, vol. 6, 8821, Nature Publishing Group, 2015, doi:<a href="https://doi.org/10.1038/ncomms9821">10.1038/ncomms9821</a>.
  short: Q. Chen, Y. Liu, S. Maere, E. Lee, G. Van Isterdael, Z. Xie, W. Xuan, J.
    Lucas, V. Vassileva, S. Kitakura, P. Marhavý, K.T. Wabnik, N. Geldner, E. Benková,
    J. Le, H. Fukaki, E. Grotewold, C. Li, J. Friml, F. Sack, T. Beeckman, S. Vanneste,
    Nature Communications 6 (2015).
date_created: 2018-12-11T11:52:48Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2025-09-22T14:28:09Z
day: '18'
ddc:
- '580'
department:
- _id: EvBe
- _id: JiFr
doi: 10.1038/ncomms9821
external_id:
  isi:
  - '000366295500007'
file:
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  date_created: 2018-12-12T10:14:32Z
  date_updated: 2020-07-14T12:45:02Z
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file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: '         6'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5597'
pubrep_id: '477'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A coherent transcriptional feed-forward motif model for mediating auxin-sensitive
  PIN3 expression during lateral root development
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2015'
...