---
res:
  bibo_abstract:
  - The immune response relies on the migration of leukocytes and on their ability
    to stop in precise anatomical locations to fulfil their task. How leukocyte migration
    and function are coordinated is unknown. Here we show that in immature dendritic
    cells, which patrol their environment by engulfing extracellular material, cell
    migration and antigen capture are antagonistic. This antagonism results from transient
    enrichment of myosin IIA at the cell front, which disrupts the back-to-front gradient
    of the motor protein, slowing down locomotion but promoting antigen capture. We
    further highlight that myosin IIA enrichment at the cell front requires the MHC
    class II-associated invariant chain (Ii). Thus, by controlling myosin IIA localization,
    Ii imposes on dendritic cells an intermittent antigen capture behaviour that might
    facilitate environment patrolling. We propose that the requirement for myosin
    II in both cell migration and specific cell functions may provide a general mechanism
    for their coordination in time and space.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Mélanie
      foaf_name: Chabaud, Mélanie
      foaf_surname: Chabaud
  - foaf_Person:
      foaf_givenName: Mélina
      foaf_name: Heuzé, Mélina
      foaf_surname: Heuzé
  - foaf_Person:
      foaf_givenName: Marine
      foaf_name: Bretou, Marine
      foaf_surname: Bretou
  - foaf_Person:
      foaf_givenName: Pablo
      foaf_name: Vargas, Pablo
      foaf_surname: Vargas
  - foaf_Person:
      foaf_givenName: Paolo
      foaf_name: Maiuri, Paolo
      foaf_surname: Maiuri
  - foaf_Person:
      foaf_givenName: Paola
      foaf_name: Solanes, Paola
      foaf_surname: Solanes
  - foaf_Person:
      foaf_givenName: Mathieu
      foaf_name: Maurin, Mathieu
      foaf_surname: Maurin
  - foaf_Person:
      foaf_givenName: Emmanuel
      foaf_name: Terriac, Emmanuel
      foaf_surname: Terriac
  - foaf_Person:
      foaf_givenName: Maël
      foaf_name: Le Berre, Maël
      foaf_surname: Le Berre
  - foaf_Person:
      foaf_givenName: Danielle
      foaf_name: Lankar, Danielle
      foaf_surname: Lankar
  - foaf_Person:
      foaf_givenName: Tristan
      foaf_name: Piolot, Tristan
      foaf_surname: Piolot
  - foaf_Person:
      foaf_givenName: Robert
      foaf_name: Adelstein, Robert
      foaf_surname: Adelstein
  - foaf_Person:
      foaf_givenName: Yingfan
      foaf_name: Zhang, Yingfan
      foaf_surname: Zhang
  - foaf_Person:
      foaf_givenName: Michael K
      foaf_name: Sixt, Michael K
      foaf_surname: Sixt
      foaf_workInfoHomepage: http://www.librecat.org/personId=41E9FBEA-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-6620-9179
  - foaf_Person:
      foaf_givenName: Jordan
      foaf_name: Jacobelli, Jordan
      foaf_surname: Jacobelli
  - foaf_Person:
      foaf_givenName: Olivier
      foaf_name: Bénichou, Olivier
      foaf_surname: Bénichou
  - foaf_Person:
      foaf_givenName: Raphaël
      foaf_name: Voituriez, Raphaël
      foaf_surname: Voituriez
  - foaf_Person:
      foaf_givenName: Matthieu
      foaf_name: Piel, Matthieu
      foaf_surname: Piel
  - foaf_Person:
      foaf_givenName: Ana
      foaf_name: Lennon Duménil, Ana
      foaf_surname: Lennon Duménil
  bibo_doi: 10.1038/ncomms8526
  bibo_volume: 6
  dct_date: 2015^xs_gYear
  dct_identifier:
  - UT:000357179400003
  dct_language: eng
  dct_publisher: Nature Publishing Group@
  dct_title: Cell migration and antigen capture are antagonistic processes coupled
    by myosin II in dendritic cells@
...