conference paper published yes Sergiy Bogomolov author 369D9A44-F248-11E8-B48F-1D18A9856A870000-0002-0686-0365 Christian Schilling author 3A2F4DCE-F248-11E8-B48F-1D18A9856A870000-0003-3658-1065 Ezio Bartocci author Grégory Batt author Hui Kong author 3BDE25AA-F248-11E8-B48F-1D18A9856A870000-0002-3066-6941 Radu Grosu author ToHe department HVC: Haifa Verification Conference Quantitative Reactive Modeling project Formal methods for the design and analysis of complex systems project Rigorous Systems Engineering project Multiaffine hybrid automata (MHA) represent a powerful formalism to model complex dynamical systems. This formalism is particularly suited for the representation of biological systems which often exhibit highly non-linear behavior. In this paper, we consider the problem of parameter identification for MHA. We present an abstraction of MHA based on linear hybrid automata, which can be analyzed by the SpaceEx model checker. This abstraction enables a precise handling of time-dependent properties. We demonstrate the potential of our approach on a model of a genetic regulatory network and a myocyte model. https://research-explorer.ista.ac.at/download/1605/7851/2015_LNCS_Bogomolov.pdf application/pdfno Springer2015Haifa, Israel eng 10.1007/978-3-319-26287-1_2 943419 - 35 Bogomolov, Sergiy, Christian Schilling, Ezio Bartocci, Grégory Batt, Hui Kong, and Radu Grosu. “Abstraction-Based Parameter Synthesis for Multiaffine Systems,” 9434:19–35. Springer, 2015. <a href="https://doi.org/10.1007/978-3-319-26287-1_2">https://doi.org/10.1007/978-3-319-26287-1_2</a>. Bogomolov, S., Schilling, C., Bartocci, E., Batt, G., Kong, H., &#38; Grosu, R. (2015). Abstraction-based parameter synthesis for multiaffine systems (Vol. 9434, pp. 19–35). Presented at the HVC: Haifa Verification Conference, Haifa, Israel: Springer. <a href="https://doi.org/10.1007/978-3-319-26287-1_2">https://doi.org/10.1007/978-3-319-26287-1_2</a> Bogomolov S, Schilling C, Bartocci E, Batt G, Kong H, Grosu R. 2015. Abstraction-based parameter synthesis for multiaffine systems. HVC: Haifa Verification Conference, LNCS, vol. 9434, 19–35. S. Bogomolov, C. Schilling, E. Bartocci, G. Batt, H. Kong, and R. Grosu, “Abstraction-based parameter synthesis for multiaffine systems,” presented at the HVC: Haifa Verification Conference, Haifa, Israel, 2015, vol. 9434, pp. 19–35. S. Bogomolov, C. Schilling, E. Bartocci, G. Batt, H. Kong, R. Grosu, in:, Springer, 2015, pp. 19–35. Bogomolov, Sergiy, et al. <i>Abstraction-Based Parameter Synthesis for Multiaffine Systems</i>. Vol. 9434, Springer, 2015, pp. 19–35, doi:<a href="https://doi.org/10.1007/978-3-319-26287-1_2">10.1007/978-3-319-26287-1_2</a>. Bogomolov S, Schilling C, Bartocci E, Batt G, Kong H, Grosu R. Abstraction-based parameter synthesis for multiaffine systems. In: Vol 9434. Springer; 2015:19-35. doi:<a href="https://doi.org/10.1007/978-3-319-26287-1_2">10.1007/978-3-319-26287-1_2</a> 16052018-12-11T11:52:59Z2025-04-15T06:26:03Z