---
res:
  bibo_abstract:
  - "Background\r\nPhotosynthetic cyanobacteria are attractive for a range of biotechnological
    applications including biofuel production. However, due to slow growth, screening
    of mutant libraries using microtiter plates is not feasible.\r\nResults\r\nWe
    present a method for high-throughput, single-cell analysis and sorting of genetically
    engineered l-lactate-producing strains of Synechocystis sp. PCC6803. A microfluidic
    device is used to encapsulate single cells in picoliter droplets, assay the droplets
    for l-lactate production, and sort strains with high productivity. We demonstrate
    the separation of low- and high-producing reference strains, as well as enrichment
    of a more productive l-lactate-synthesizing population after UV-induced mutagenesis.
    The droplet platform also revealed population heterogeneity in photosynthetic
    growth and lactate production, as well as the presence of metabolically stalled
    cells.\r\nConclusions\r\nThe workflow will facilitate metabolic engineering and
    directed evolution studies and will be useful in studies of cyanobacteria biochemistry
    and physiology.\r\n@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Petter
      foaf_name: Hammar, Petter
      foaf_surname: Hammar
  - foaf_Person:
      foaf_givenName: Andreas
      foaf_name: Angermayr, Andreas
      foaf_surname: Angermayr
      foaf_workInfoHomepage: http://www.librecat.org/personId=4677C796-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8619-2223
  - foaf_Person:
      foaf_givenName: Staffan
      foaf_name: Sjostrom, Staffan
      foaf_surname: Sjostrom
  - foaf_Person:
      foaf_givenName: Josefin
      foaf_name: Van Der Meer, Josefin
      foaf_surname: Van Der Meer
  - foaf_Person:
      foaf_givenName: Klaas
      foaf_name: Hellingwerf, Klaas
      foaf_surname: Hellingwerf
  - foaf_Person:
      foaf_givenName: Elton
      foaf_name: Hudson, Elton
      foaf_surname: Hudson
  - foaf_Person:
      foaf_givenName: Hakaan
      foaf_name: Joensson, Hakaan
      foaf_surname: Joensson
  bibo_doi: 10.1186/s13068-015-0380-2
  bibo_issue: '1'
  bibo_volume: 8
  dct_date: 2015^xs_gYear
  dct_identifier:
  - UT:000365784000009
  dct_language: eng
  dct_publisher: BioMed Central@
  dct_title: Single-cell screening of photosynthetic growth and lactate production
    by cyanobacteria@
...