{"quality_controlled":"1","year":"2022","external_id":{"pmid":["35050671"]},"abstract":[{"text":"Fertilization of an egg by multiple sperm (polyspermy) leads to lethal genome imbalance and chromosome segregation defects. In Arabidopsis thaliana, the block to polyspermy is facilitated by a mechanism that prevents polytubey (the arrival of multiple pollen tubes to one ovule). We show here that FERONIA, ANJEA, and HERCULES RECEPTOR KINASE 1 receptor-like kinases located at the septum interact with pollen tube–specific RALF6, 7, 16, 36, and 37 peptide ligands to establish this polytubey block. The same combination of RALF (rapid alkalinization factor) peptides and receptor complexes controls pollen tube reception and rupture inside the targeted ovule. Pollen tube rupture releases the polytubey block at the septum, which allows the emergence of secondary pollen tubes upon fertilization failure. Thus, orchestrated steps in the fertilization process in Arabidopsis are coordinated by the same signaling components to guarantee and optimize reproductive success.","lang":"eng"}],"publication_status":"published","publisher":"American Association for the Advancement of Science","author":[{"full_name":"Zhong, Sheng","first_name":"Sheng","last_name":"Zhong"},{"last_name":"Li","full_name":"Li, Ling","first_name":"Ling"},{"full_name":"Wang, Zhijuan","first_name":"Zhijuan","last_name":"Wang"},{"full_name":"Ge, Zengxiang","first_name":"Zengxiang","id":"f43371a3-09ff-11eb-8013-bd0c6a2f6de8","orcid":"0000-0001-9381-3577","last_name":"Ge"},{"last_name":"Li","first_name":"Qiyun","full_name":"Li, Qiyun"},{"last_name":"Bleckmann","first_name":"Andrea","full_name":"Bleckmann, Andrea"},{"last_name":"Wang","first_name":"Jizong","full_name":"Wang, Jizong"},{"first_name":"Zihan","full_name":"Song, Zihan","last_name":"Song"},{"last_name":"Shi","first_name":"Yihao","full_name":"Shi, Yihao"},{"full_name":"Liu, Tianxu","first_name":"Tianxu","last_name":"Liu"},{"last_name":"Li","full_name":"Li, Luhan","first_name":"Luhan"},{"full_name":"Zhou, Huabin","first_name":"Huabin","last_name":"Zhou"},{"full_name":"Wang, Yanyan","first_name":"Yanyan","last_name":"Wang"},{"first_name":"Li","full_name":"Zhang, Li","last_name":"Zhang"},{"last_name":"Wu","full_name":"Wu, Hen-Ming","first_name":"Hen-Ming"},{"full_name":"Lai, Luhua","first_name":"Luhua","last_name":"Lai"},{"first_name":"Hongya","full_name":"Gu, Hongya","last_name":"Gu"},{"last_name":"Dong","full_name":"Dong, Juan","first_name":"Juan"},{"last_name":"Cheung","first_name":"Alice Y.","full_name":"Cheung, Alice Y."},{"last_name":"Dresselhaus","first_name":"Thomas","full_name":"Dresselhaus, Thomas"},{"last_name":"Qu","full_name":"Qu, Li-Jia","first_name":"Li-Jia"}],"_id":"17069","publication":"Science","pmid":1,"language":[{"iso":"eng"}],"date_created":"2024-05-29T06:11:10Z","status":"public","oa_version":"None","article_type":"original","month":"01","type":"journal_article","department":[{"_id":"JiFr"}],"volume":375,"publication_identifier":{"issn":["0036-8075"],"eissn":["1095-9203"]},"acknowledgement":"We thank D. Ye for providing fer-4 and myb97 myb101 myb120 mutant seeds; L. Smith for sharing anj, herk1, anj herk1, and fer anj herk1 mutant seeds; J. F. Harper for providing aca9 mutant seeds; and C. Li and Q. Duan for sharing fer+/− mutant seeds.\r\nL.-J.Q. was funded by the National Natural Science Foundation of China (grant nos. 31991202, 31830004, 31620103903, and 31621001), S.Z. was supported by the Young Elite Scientists Sponsorship Program by the China Association of Science and Technology (2019QNRC001), Z.G. was supported by a NSFC Young Scientists Fund (31900161), A.Y.C. was funded by the US Natural Science Foundation (IOS-1645854, MCB-1715764, and MCB-0955910), J.D. was funded by the National Institute of Health (R01GM109080), and T.D. was supported by the German Research Foundation DFG (SFB924).","page":"290-296","issue":"6578","title":"RALF peptide signaling controls the polytubey block in Arabidopsis","intvolume":"       375","scopus_import":"1","date_updated":"2024-08-05T10:21:03Z","day":"20","citation":{"ieee":"S. Zhong <i>et al.</i>, “RALF peptide signaling controls the polytubey block in Arabidopsis,” <i>Science</i>, vol. 375, no. 6578. American Association for the Advancement of Science, pp. 290–296, 2022.","short":"S. Zhong, L. Li, Z. Wang, Z. Ge, Q. Li, A. Bleckmann, J. Wang, Z. Song, Y. Shi, T. Liu, L. Li, H. Zhou, Y. Wang, L. Zhang, H.-M. Wu, L. Lai, H. Gu, J. Dong, A.Y. Cheung, T. Dresselhaus, L.-J. Qu, Science 375 (2022) 290–296.","ista":"Zhong S, Li L, Wang Z, Ge Z, Li Q, Bleckmann A, Wang J, Song Z, Shi Y, Liu T, Li L, Zhou H, Wang Y, Zhang L, Wu H-M, Lai L, Gu H, Dong J, Cheung AY, Dresselhaus T, Qu L-J. 2022. RALF peptide signaling controls the polytubey block in Arabidopsis. Science. 375(6578), 290–296.","ama":"Zhong S, Li L, Wang Z, et al. RALF peptide signaling controls the polytubey block in Arabidopsis. <i>Science</i>. 2022;375(6578):290-296. doi:<a href=\"https://doi.org/10.1126/science.abl4683\">10.1126/science.abl4683</a>","mla":"Zhong, Sheng, et al. “RALF Peptide Signaling Controls the Polytubey Block in Arabidopsis.” <i>Science</i>, vol. 375, no. 6578, American Association for the Advancement of Science, 2022, pp. 290–96, doi:<a href=\"https://doi.org/10.1126/science.abl4683\">10.1126/science.abl4683</a>.","apa":"Zhong, S., Li, L., Wang, Z., Ge, Z., Li, Q., Bleckmann, A., … Qu, L.-J. (2022). RALF peptide signaling controls the polytubey block in Arabidopsis. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.abl4683\">https://doi.org/10.1126/science.abl4683</a>","chicago":"Zhong, Sheng, Ling Li, Zhijuan Wang, Zengxiang Ge, Qiyun Li, Andrea Bleckmann, Jizong Wang, et al. “RALF Peptide Signaling Controls the Polytubey Block in Arabidopsis.” <i>Science</i>. American Association for the Advancement of Science, 2022. <a href=\"https://doi.org/10.1126/science.abl4683\">https://doi.org/10.1126/science.abl4683</a>."},"date_published":"2022-01-20T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1126/science.abl4683","article_processing_charge":"No"}