---
OA_place: repository
OA_type: green
_id: '17069'
abstract:
- lang: eng
text: Fertilization of an egg by multiple sperm (polyspermy) leads to lethal genome
imbalance and chromosome segregation defects. In Arabidopsis thaliana, the block
to polyspermy is facilitated by a mechanism that prevents polytubey (the arrival
of multiple pollen tubes to one ovule). We show here that FERONIA, ANJEA, and
HERCULES RECEPTOR KINASE 1 receptor-like kinases located at the septum interact
with pollen tube–specific RALF6, 7, 16, 36, and 37 peptide ligands to establish
this polytubey block. The same combination of RALF (rapid alkalinization factor)
peptides and receptor complexes controls pollen tube reception and rupture inside
the targeted ovule. Pollen tube rupture releases the polytubey block at the septum,
which allows the emergence of secondary pollen tubes upon fertilization failure.
Thus, orchestrated steps in the fertilization process in Arabidopsis are coordinated
by the same signaling components to guarantee and optimize reproductive success.
acknowledgement: "We thank D. Ye for providing fer-4 and myb97 myb101 myb120 mutant
seeds; L. Smith for sharing anj, herk1, anj herk1, and fer anj herk1 mutant seeds;
J. F. Harper for providing aca9 mutant seeds; and C. Li and Q. Duan for sharing
fer+/− mutant seeds.\r\nL.-J.Q. was funded by the National Natural Science Foundation
of China (grant nos. 31991202, 31830004, 31620103903, and 31621001), S.Z. was supported
by the Young Elite Scientists Sponsorship Program by the China Association of Science
and Technology (2019QNRC001), Z.G. was supported by a NSFC Young Scientists Fund
(31900161), A.Y.C. was funded by the US Natural Science Foundation (IOS-1645854,
MCB-1715764, and MCB-0955910), J.D. was funded by the National Institute of Health
(R01GM109080), and T.D. was supported by the German Research Foundation DFG (SFB924)."
article_processing_charge: No
article_type: original
author:
- first_name: Sheng
full_name: Zhong, Sheng
last_name: Zhong
- first_name: Ling
full_name: Li, Ling
last_name: Li
- first_name: Zhijuan
full_name: Wang, Zhijuan
last_name: Wang
- first_name: Zengxiang
full_name: Ge, Zengxiang
id: f43371a3-09ff-11eb-8013-bd0c6a2f6de8
last_name: Ge
orcid: 0000-0001-9381-3577
- first_name: Qiyun
full_name: Li, Qiyun
last_name: Li
- first_name: Andrea
full_name: Bleckmann, Andrea
last_name: Bleckmann
- first_name: Jizong
full_name: Wang, Jizong
last_name: Wang
- first_name: Zihan
full_name: Song, Zihan
last_name: Song
- first_name: Yihao
full_name: Shi, Yihao
last_name: Shi
- first_name: Tianxu
full_name: Liu, Tianxu
last_name: Liu
- first_name: Luhan
full_name: Li, Luhan
last_name: Li
- first_name: Huabin
full_name: Zhou, Huabin
last_name: Zhou
- first_name: Yanyan
full_name: Wang, Yanyan
last_name: Wang
- first_name: Li
full_name: Zhang, Li
last_name: Zhang
- first_name: Hen-Ming
full_name: Wu, Hen-Ming
last_name: Wu
- first_name: Luhua
full_name: Lai, Luhua
last_name: Lai
- first_name: Hongya
full_name: Gu, Hongya
last_name: Gu
- first_name: Juan
full_name: Dong, Juan
last_name: Dong
- first_name: Alice Y.
full_name: Cheung, Alice Y.
last_name: Cheung
- first_name: Thomas
full_name: Dresselhaus, Thomas
last_name: Dresselhaus
- first_name: Li-Jia
full_name: Qu, Li-Jia
last_name: Qu
citation:
ama: Zhong S, Li L, Wang Z, et al. RALF peptide signaling controls the polytubey
block in Arabidopsis. Science. 2022;375(6578):290-296. doi:10.1126/science.abl4683
apa: Zhong, S., Li, L., Wang, Z., Ge, Z., Li, Q., Bleckmann, A., … Qu, L.-J. (2022).
RALF peptide signaling controls the polytubey block in Arabidopsis. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.abl4683
chicago: Zhong, Sheng, Ling Li, Zhijuan Wang, Zengxiang Ge, Qiyun Li, Andrea Bleckmann,
Jizong Wang, et al. “RALF Peptide Signaling Controls the Polytubey Block in Arabidopsis.”
Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.abl4683.
ieee: S. Zhong et al., “RALF peptide signaling controls the polytubey block
in Arabidopsis,” Science, vol. 375, no. 6578. American Association for
the Advancement of Science, pp. 290–296, 2022.
ista: Zhong S, Li L, Wang Z, Ge Z, Li Q, Bleckmann A, Wang J, Song Z, Shi Y, Liu
T, Li L, Zhou H, Wang Y, Zhang L, Wu H-M, Lai L, Gu H, Dong J, Cheung AY, Dresselhaus
T, Qu L-J. 2022. RALF peptide signaling controls the polytubey block in Arabidopsis.
Science. 375(6578), 290–296.
mla: Zhong, Sheng, et al. “RALF Peptide Signaling Controls the Polytubey Block in
Arabidopsis.” Science, vol. 375, no. 6578, American Association for the
Advancement of Science, 2022, pp. 290–96, doi:10.1126/science.abl4683.
short: S. Zhong, L. Li, Z. Wang, Z. Ge, Q. Li, A. Bleckmann, J. Wang, Z. Song, Y.
Shi, T. Liu, L. Li, H. Zhou, Y. Wang, L. Zhang, H.-M. Wu, L. Lai, H. Gu, J. Dong,
A.Y. Cheung, T. Dresselhaus, L.-J. Qu, Science 375 (2022) 290–296.
date_created: 2024-05-29T06:11:10Z
date_published: 2022-01-20T00:00:00Z
date_updated: 2025-04-24T11:39:46Z
day: '20'
department:
- _id: JiFr
doi: 10.1126/science.abl4683
external_id:
pmid:
- '35050671'
intvolume: ' 375'
issue: '6578'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040003
month: '01'
oa: 1
oa_version: Submitted Version
page: 290-296
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: RALF peptide signaling controls the polytubey block in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 375
year: '2022'
...