article published Anna Kicheva author 3959A2A0-F248-11E8-B48F-1D18A9856A870000-0003-4509-4998 Marcos González Gaitán author Two key processes are in the basis of morphogenesis: the spatial allocation of cell types in fields of naïve cells and the regulation of growth. Both are controlled by morphogens, which activate target genes in the growing tissue in a concentration-dependent manner. Thus the morphogen model is an intrinsically quantitative concept. However, quantitative studies were performed only in recent years on two morphogens: Bicoid and Decapentaplegic. This review covers quantitative aspects of the formation and precision of the Decapentaplegic morphogen gradient. The morphogen gradient concept is transitioning from a soft definition to a precise idea of what the gradient could really do. Elsevier2008 10.1016/j.ceb.2008.01.008 202137 - 143 yes Kicheva, A., &#38; González Gaitán, M. (2008). The Decapentaplegic morphogen gradient a precise definition. <i>Current Opinion in Cell Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.ceb.2008.01.008">https://doi.org/10.1016/j.ceb.2008.01.008</a> Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient a Precise Definition.” <i>Current Opinion in Cell Biology</i>. Elsevier, 2008. <a href="https://doi.org/10.1016/j.ceb.2008.01.008">https://doi.org/10.1016/j.ceb.2008.01.008</a>. Kicheva A, González Gaitán M. The Decapentaplegic morphogen gradient a precise definition. <i>Current Opinion in Cell Biology</i>. 2008;20(2):137-143. doi:<a href="https://doi.org/10.1016/j.ceb.2008.01.008">10.1016/j.ceb.2008.01.008</a> Kicheva A, González Gaitán M. 2008. The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. 20(2), 137–143. A. Kicheva, M. González Gaitán, Current Opinion in Cell Biology 20 (2008) 137–143. A. Kicheva and M. González Gaitán, “The Decapentaplegic morphogen gradient a precise definition,” <i>Current Opinion in Cell Biology</i>, vol. 20, no. 2. Elsevier, pp. 137–143, 2008. Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient a Precise Definition.” <i>Current Opinion in Cell Biology</i>, vol. 20, no. 2, Elsevier, 2008, pp. 137–43, doi:<a href="https://doi.org/10.1016/j.ceb.2008.01.008">10.1016/j.ceb.2008.01.008</a>. 17172018-12-11T11:53:38Z2021-01-12T06:52:44Z