{"year":"2024","publication":"Science China Life Sciences","scopus_import":"1","acknowledgement":"We thank Prof. Kang Chong from Institute of Botany, the Chinese Academy of Science for valuable comments, Dr. Haoran Li for the help with western blot of H3K36me3 in Tasdg8-cr lines. This research was supported by National Natural Science Foundation (31970529), Beijing Natural Science Foundation Outstanding Youth Project (JQ23026), National Key Research and Development Program of China (2021YFD1201500), and the Major Basic Research Program of Shandong Natural Science Foundation (ZR2019ZD15).","date_created":"2024-07-21T22:01:02Z","article_processing_charge":"No","department":[{"_id":"XiFe"}],"title":"Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat","article_type":"original","date_updated":"2024-07-22T06:26:49Z","day":"08","author":[{"first_name":"Xuemei","last_name":"Liu","full_name":"Liu, Xuemei"},{"full_name":"Deng, Min","last_name":"Deng","first_name":"Min"},{"full_name":"Shi, Bingxin","last_name":"Shi","first_name":"Bingxin"},{"first_name":"Kehui","last_name":"Zhu","full_name":"Zhu, Kehui"},{"full_name":"Chen, Jinchao","first_name":"Jinchao","last_name":"Chen"},{"first_name":"Shujuan","id":"9724dd9d-f591-11ee-bd51-e97ed0652286","last_name":"Xu","full_name":"Xu, Shujuan"},{"full_name":"Bie, Xiaomin","first_name":"Xiaomin","last_name":"Bie"},{"last_name":"Zhang","first_name":"Xiansheng","full_name":"Zhang, Xiansheng"},{"first_name":"Xuelei","last_name":"Lin","full_name":"Lin, Xuelei"},{"full_name":"Xiao, Jun","last_name":"Xiao","first_name":"Jun"}],"doi":"10.1007/s11427-024-2664-0","publisher":"Springer Nature","quality_controlled":"1","date_published":"2024-07-08T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"17285","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1869-1889"],"issn":["1674-7305"]},"abstract":[{"lang":"eng","text":"Winter plants rely on vernalization, a crucial process for adapting to cold conditions and ensuring successful reproduction. However, understanding the role of histone modifications in guiding the vernalization process in winter wheat remains limited. In this study, we investigated the transcriptome and chromatin dynamics in the shoot apex throughout the life cycle of winter wheat in the field. Two core histone modifications, H3K27me3 and H3K36me3, exhibited opposite patterns on the key vernalization gene VERNALIZATION1 (VRN1), correlating with its induction during cold exposure. Moreover, the H3K36me3 level remained high at VRN1 after cold exposure, which may maintain its active state. Mutations in FERTILIZATION-INDEPENDENT ENDOSPERM (TaFIE) and SET DOMAIN GROUP 8/EARLY FLOWERING IN SHORT DAYS (TaSDG8/TaEFS), components of the writer complex for H3K27me3 and H3K36me3, respectively, affected flowering time. Intriguingly, VRN1 lost its high expression after the cold exposure memory in the absence of H3K36me3. During embryo development, VRN1 was silenced with the removal of active histone modifications in both winter and spring wheat, with selective restoration of H3K27me3 in winter wheat. The mutant of Tafie-cr-87, a component of H3K27me3 “writer” complex, did not influence the silence of VRN1 during embryo development, but rather attenuated the cold exposure requirement of winter wheat. Integrating gene expression with H3K27me3 and H3K36me3 patterns identified potential regulators of flowering. This study unveils distinct roles of H3K27me3 and H3K36me3 in controlling vernalization response, maintenance, and resetting in winter wheat."}],"status":"public","type":"journal_article","month":"07","oa_version":"None","citation":{"mla":"Liu, Xuemei, et al. “Distinct Roles of H3K27me3 and H3K36me3 in Vernalization Response, Maintenance, and Resetting in Winter Wheat.” <i>Science China Life Sciences</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s11427-024-2664-0\">10.1007/s11427-024-2664-0</a>.","short":"X. Liu, M. Deng, B. Shi, K. Zhu, J. Chen, S. Xu, X. Bie, X. Zhang, X. Lin, J. Xiao, Science China Life Sciences (2024).","ieee":"X. Liu <i>et al.</i>, “Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat,” <i>Science China Life Sciences</i>. Springer Nature, 2024.","ama":"Liu X, Deng M, Shi B, et al. Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat. <i>Science China Life Sciences</i>. 2024. doi:<a href=\"https://doi.org/10.1007/s11427-024-2664-0\">10.1007/s11427-024-2664-0</a>","apa":"Liu, X., Deng, M., Shi, B., Zhu, K., Chen, J., Xu, S., … Xiao, J. (2024). Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat. <i>Science China Life Sciences</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11427-024-2664-0\">https://doi.org/10.1007/s11427-024-2664-0</a>","chicago":"Liu, Xuemei, Min Deng, Bingxin Shi, Kehui Zhu, Jinchao Chen, Shujuan Xu, Xiaomin Bie, Xiansheng Zhang, Xuelei Lin, and Jun Xiao. “Distinct Roles of H3K27me3 and H3K36me3 in Vernalization Response, Maintenance, and Resetting in Winter Wheat.” <i>Science China Life Sciences</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s11427-024-2664-0\">https://doi.org/10.1007/s11427-024-2664-0</a>.","ista":"Liu X, Deng M, Shi B, Zhu K, Chen J, Xu S, Bie X, Zhang X, Lin X, Xiao J. 2024. Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat. Science China Life Sciences."},"publication_status":"epub_ahead"}