---
OA_place: repository
OA_type: green
_id: '17285'
abstract:
- lang: eng
  text: Winter plants rely on vernalization, a crucial process for adapting to cold
    conditions and ensuring successful reproduction. However, understanding the role
    of histone modifications in guiding the vernalization process in winter wheat
    remains limited. In this study, we investigated the transcriptome and chromatin
    dynamics in the shoot apex throughout the life cycle of winter wheat in the field.
    Two core histone modifications, H3K27me3 and H3K36me3, exhibited opposite patterns
    on the key vernalization gene VERNALIZATION1 (VRN1), correlating with its induction
    during cold exposure. Moreover, the H3K36me3 level remained high at VRN1 after
    cold exposure, which may maintain its active state. Mutations in FERTILIZATION-INDEPENDENT
    ENDOSPERM (TaFIE) and SET DOMAIN GROUP 8/EARLY FLOWERING IN SHORT DAYS (TaSDG8/TaEFS),
    components of the writer complex for H3K27me3 and H3K36me3, respectively, affected
    flowering time. Intriguingly, VRN1 lost its high expression after the cold exposure
    memory in the absence of H3K36me3. During embryo development, VRN1 was silenced
    with the removal of active histone modifications in both winter and spring wheat,
    with selective restoration of H3K27me3 in winter wheat. The mutant of Tafie-cr-87,
    a component of H3K27me3 “writer” complex, did not influence the silence of VRN1
    during embryo development, but rather attenuated the cold exposure requirement
    of winter wheat. Integrating gene expression with H3K27me3 and H3K36me3 patterns
    identified potential regulators of flowering. This study unveils distinct roles
    of H3K27me3 and H3K36me3 in controlling vernalization response, maintenance, and
    resetting in winter wheat.
acknowledgement: We thank Prof. Kang Chong from Institute of Botany, the Chinese Academy
  of Science for valuable comments, Dr. Haoran Li for the help with western blot of
  H3K36me3 in Tasdg8-cr lines. This research was supported by National Natural Science
  Foundation (31970529), Beijing Natural Science Foundation Outstanding Youth Project
  (JQ23026), National Key Research and Development Program of China (2021YFD1201500),
  and the Major Basic Research Program of Shandong Natural Science Foundation (ZR2019ZD15).
article_processing_charge: No
article_type: original
author:
- first_name: Xuemei
  full_name: Liu, Xuemei
  last_name: Liu
- first_name: Min
  full_name: Deng, Min
  last_name: Deng
- first_name: Bingxin
  full_name: Shi, Bingxin
  last_name: Shi
- first_name: Kehui
  full_name: Zhu, Kehui
  last_name: Zhu
- first_name: Jinchao
  full_name: Chen, Jinchao
  last_name: Chen
- first_name: Shujuan
  full_name: Xu, Shujuan
  id: 9724dd9d-f591-11ee-bd51-e97ed0652286
  last_name: Xu
- first_name: Xiaomin
  full_name: Bie, Xiaomin
  last_name: Bie
- first_name: Xiansheng
  full_name: Zhang, Xiansheng
  last_name: Zhang
- first_name: Xuelei
  full_name: Lin, Xuelei
  last_name: Lin
- first_name: Jun
  full_name: Xiao, Jun
  last_name: Xiao
citation:
  ama: Liu X, Deng M, Shi B, et al. Distinct roles of H3K27me3 and H3K36me3 in vernalization
    response, maintenance, and resetting in winter wheat. <i>Science China Life Sciences</i>.
    2024;67:2251-2266. doi:<a href="https://doi.org/10.1007/s11427-024-2664-0">10.1007/s11427-024-2664-0</a>
  apa: Liu, X., Deng, M., Shi, B., Zhu, K., Chen, J., Xu, S., … Xiao, J. (2024). Distinct
    roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting
    in winter wheat. <i>Science China Life Sciences</i>. Springer Nature. <a href="https://doi.org/10.1007/s11427-024-2664-0">https://doi.org/10.1007/s11427-024-2664-0</a>
  chicago: Liu, Xuemei, Min Deng, Bingxin Shi, Kehui Zhu, Jinchao Chen, Shujuan Xu,
    Xiaomin Bie, Xiansheng Zhang, Xuelei Lin, and Jun Xiao. “Distinct Roles of H3K27me3
    and H3K36me3 in Vernalization Response, Maintenance, and Resetting in Winter Wheat.”
    <i>Science China Life Sciences</i>. Springer Nature, 2024. <a href="https://doi.org/10.1007/s11427-024-2664-0">https://doi.org/10.1007/s11427-024-2664-0</a>.
  ieee: X. Liu <i>et al.</i>, “Distinct roles of H3K27me3 and H3K36me3 in vernalization
    response, maintenance, and resetting in winter wheat,” <i>Science China Life Sciences</i>,
    vol. 67. Springer Nature, pp. 2251–2266, 2024.
  ista: Liu X, Deng M, Shi B, Zhu K, Chen J, Xu S, Bie X, Zhang X, Lin X, Xiao J.
    2024. Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance,
    and resetting in winter wheat. Science China Life Sciences. 67, 2251–2266.
  mla: Liu, Xuemei, et al. “Distinct Roles of H3K27me3 and H3K36me3 in Vernalization
    Response, Maintenance, and Resetting in Winter Wheat.” <i>Science China Life Sciences</i>,
    vol. 67, Springer Nature, 2024, pp. 2251–66, doi:<a href="https://doi.org/10.1007/s11427-024-2664-0">10.1007/s11427-024-2664-0</a>.
  short: X. Liu, M. Deng, B. Shi, K. Zhu, J. Chen, S. Xu, X. Bie, X. Zhang, X. Lin,
    J. Xiao, Science China Life Sciences 67 (2024) 2251–2266.
date_created: 2024-07-21T22:01:02Z
date_published: 2024-10-01T00:00:00Z
date_updated: 2025-09-08T08:15:08Z
day: '01'
department:
- _id: XiFe
doi: 10.1007/s11427-024-2664-0
external_id:
  isi:
  - '001268807700002'
  pmid:
  - '38987431'
intvolume: '        67'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2023.12.19.572364
month: '10'
oa: 1
oa_version: Preprint
page: 2251-2266
pmid: 1
publication: Science China Life Sciences
publication_identifier:
  eissn:
  - 1869-1889
  issn:
  - 1674-7305
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance,
  and resetting in winter wheat
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 67
year: '2024'
...