database Marwan N Elkrewi author 0B46FACA-A8E1-11E9-9BD3-79D1E56974250000-0002-5328-7231 Beatriz Vicoso author 49E1C5C6-F248-11E8-B48F-1D18A9856A870000-0002-4579-8306 GradSch department BeVi department The highjacking of meiosis for asexual reproduction project This is the supplementary data for the paper titled "Single-nucleus atlas of the Artemia female reproductive system suggests germline repression of the Z chromosome", where we described the generation and analysis of single-nucleus expression and chromatin-accessibility data from the female reproductive system of Artemia franciscana. We compared our dataset to the published Drosophila single-nucleus data (over 400 million years of divergence) and highlighted the extreme conservation of several of the molecular pathways of oogenesis and meiosis. We found evidence of global transcriptional quiescence and chromatin condensation in late germ cells, highlighting the conserved role of this repressive stage in arthropod oogenesis. Additionally, we explored the expression patterns of the ZW sex chromosomes during oogenesis. Our data shows that the Z-chromosome is consistently downregulated in germline cells. While this is partly driven by a lack of dosage compensation in the germline, a subset of cells show stronger repression of the Z chromosome. https://research-explorer.ista.ac.at/download/17362/17394/README.txt text/plainno https://research-explorer.ista.ac.at/download/17362/17395/Data_artemia_single_nucleus_atlas.zip application/x-zip-compressedno https://creativecommons.org/licenses/by/4.0/ Institute of Science and Technology Austria2024 10.15479/AT:ISTA:17362 https://research-explorer.ista.ac.at/record/17890 Elkrewi, M. N., &#38; Vicoso, B. (2024). Data for: “Single-nucleus atlas of the Artemia female reproductive system suggests germline repression of the Z chromosome.” Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:17362">https://doi.org/10.15479/AT:ISTA:17362</a> M.N. Elkrewi, B. Vicoso, (2024). M. N. Elkrewi and B. Vicoso, “Data for: ‘Single-nucleus atlas of the Artemia female reproductive system suggests germline repression of the Z chromosome.’” Institute of Science and Technology Austria, 2024. Elkrewi, Marwan N, and Beatriz Vicoso. “Data for: ‘Single-Nucleus Atlas of the Artemia Female Reproductive System Suggests Germline Repression of the Z Chromosome.’” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/AT:ISTA:17362">https://doi.org/10.15479/AT:ISTA:17362</a>. Elkrewi MN, Vicoso B. 2024. Data for: ‘Single-nucleus atlas of the Artemia female reproductive system suggests germline repression of the Z chromosome’, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:17362">10.15479/AT:ISTA:17362</a>. Elkrewi, Marwan N., and Beatriz Vicoso. <i>Data for: “Single-Nucleus Atlas of the Artemia Female Reproductive System Suggests Germline Repression of the Z Chromosome.”</i> Institute of Science and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/AT:ISTA:17362">10.15479/AT:ISTA:17362</a>. Elkrewi MN, Vicoso B. Data for: “Single-nucleus atlas of the Artemia female reproductive system suggests germline repression of the Z chromosome.” 2024. doi:<a href="https://doi.org/10.15479/AT:ISTA:17362">10.15479/AT:ISTA:17362</a> 173622024-08-02T07:27:45Z2026-04-16T12:20:41Z