---
_id: '17362'
abstract:
- lang: eng
  text: This is the supplementary data for the paper titled "Single-nucleus atlas
    of the Artemia female reproductive system suggests germline repression of the
    Z chromosome", where we described the generation and analysis of single-nucleus
    expression and chromatin-accessibility data from the female reproductive system
    of Artemia franciscana. We compared our dataset to the published Drosophila single-nucleus
    data (over 400 million years of divergence) and highlighted the extreme conservation
    of several of the molecular pathways of oogenesis and meiosis. We found evidence
    of global transcriptional quiescence and chromatin condensation in late germ cells,
    highlighting the conserved role of this repressive stage in arthropod oogenesis.
    Additionally, we explored the expression patterns of the ZW sex chromosomes during
    oogenesis. Our data shows that the Z-chromosome is consistently downregulated
    in germline cells. While this is partly driven by a lack of dosage compensation
    in the germline, a subset of cells show stronger repression of the Z chromosome.
acknowledged_ssus:
- _id: ScienComp
article_processing_charge: No
author:
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: 'Elkrewi MN, Vicoso B. Data for: “Single-nucleus atlas of the Artemia female
    reproductive system suggests germline repression of the Z chromosome.” 2024. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:17362">10.15479/AT:ISTA:17362</a>'
  apa: 'Elkrewi, M. N., &#38; Vicoso, B. (2024). Data for: “Single-nucleus atlas of
    the Artemia female reproductive system suggests germline repression of the Z chromosome.”
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:17362">https://doi.org/10.15479/AT:ISTA:17362</a>'
  chicago: 'Elkrewi, Marwan N, and Beatriz Vicoso. “Data for: ‘Single-Nucleus Atlas
    of the Artemia Female Reproductive System Suggests Germline Repression of the
    Z Chromosome.’” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/AT:ISTA:17362">https://doi.org/10.15479/AT:ISTA:17362</a>.'
  ieee: 'M. N. Elkrewi and B. Vicoso, “Data for: ‘Single-nucleus atlas of the Artemia
    female reproductive system suggests germline repression of the Z chromosome.’”
    Institute of Science and Technology Austria, 2024.'
  ista: 'Elkrewi MN, Vicoso B. 2024. Data for: ‘Single-nucleus atlas of the Artemia
    female reproductive system suggests germline repression of the Z chromosome’,
    Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:17362">10.15479/AT:ISTA:17362</a>.'
  mla: 'Elkrewi, Marwan N., and Beatriz Vicoso. <i>Data for: “Single-Nucleus Atlas
    of the Artemia Female Reproductive System Suggests Germline Repression of the
    Z Chromosome.”</i> Institute of Science and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/AT:ISTA:17362">10.15479/AT:ISTA:17362</a>.'
  short: M.N. Elkrewi, B. Vicoso, (2024).
corr_author: '1'
date_created: 2024-08-02T07:27:45Z
date_published: 2024-08-05T00:00:00Z
date_updated: 2026-04-16T12:20:41Z
day: '05'
ddc:
- '576'
department:
- _id: GradSch
- _id: BeVi
doi: 10.15479/AT:ISTA:17362
file:
- access_level: open_access
  checksum: 26b5d41b3103f4284dd97d56e370a5b6
  content_type: text/plain
  creator: melkrewi
  date_created: 2024-08-05T22:24:18Z
  date_updated: 2024-08-05T22:24:18Z
  file_id: '17394'
  file_name: README.txt
  file_size: 2465
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 95adab5e36148015da313505e3910707
  content_type: application/x-zip-compressed
  creator: melkrewi
  date_created: 2024-08-05T23:28:52Z
  date_updated: 2024-08-05T23:28:52Z
  file_id: '17395'
  file_name: Data_artemia_single_nucleus_atlas.zip
  file_size: 2526735400
  relation: main_file
  success: 1
file_date_updated: 2024-08-05T23:28:52Z
has_accepted_license: '1'
license: https://creativecommons.org/licenses/by/4.0/
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17890'
    relation: used_in_publication
    status: public
status: public
title: 'Data for: "Single-nucleus atlas of the Artemia female reproductive system
  suggests germline repression of the Z chromosome"'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...