--- res: bibo_abstract: - Proliferating cell populations at steady-state growth often exhibit broad protein distributions with exponential tails. The sources of this variation and its universality are of much theoretical interest. Here we address the problem by asymptotic analysis of the population balance equation. We show that the steady-state distribution tail is determined by a combination of protein production and cell division and is insensitive to other model details. Under general conditions this tail is exponential with a dependence on parameters consistent with experiment. We discuss the conditions for this effect to be dominant over other sources of variation and the relation to experiments.@eng bibo_authorlist: - foaf_Person: foaf_givenName: Tamar foaf_name: Tamar Friedlander foaf_surname: Friedlander foaf_workInfoHomepage: http://www.librecat.org/personId=36A5845C-F248-11E8-B48F-1D18A9856A87 - foaf_Person: foaf_givenName: Naama foaf_name: Brenner, Naama foaf_surname: Brenner bibo_doi: 10.1103/PhysRevLett.101.018104 bibo_issue: '1' bibo_volume: 101 dct_date: 2008^xs_gYear dct_publisher: American Physical Society@ dct_title: Cellular properties and population asymptotics in the population balance equation@ ...