---
res:
  bibo_abstract:
  - To control morphogenesis, molecular regulatory networks have to interfere with
    the mechanical properties of the individual cells of developing organs and tissues,
    but how this is achieved is not well known. We study this issue here in the shoot
    meristem of higher plants, a group of undifferentiated cells where complex changes
    in growth rates and directions lead to the continuous formation of new organs
    [1, 2]. Here, we show that the plant hormone auxin plays an important role in
    this process via a dual, local effect on the extracellular matrix, the cell wall,
    which determines cell shape. Our study reveals that auxin not only causes a limited
    reduction in wall stiffness but also directly interferes with wall anisotropy
    via the regulation of cortical microtubule dynamics. We further show that to induce
    growth isotropy and organ outgrowth, auxin somehow interferes with the cortical
    microtubule-ordering activity of a network of proteins, including AUXIN BINDING
    PROTEIN 1 and KATANIN 1. Numerical simulations further indicate that the induced
    isotropy is sufficient to amplify the effects of the relatively minor changes
    in wall stiffness to promote organogenesis and the establishment of new growth
    axes in a robust manner.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Massimiliano
      foaf_name: Sassi, Massimiliano
      foaf_surname: Sassi
  - foaf_Person:
      foaf_givenName: Olivier
      foaf_name: Ali, Olivier
      foaf_surname: Ali
  - foaf_Person:
      foaf_givenName: Frédéric
      foaf_name: Boudon, Frédéric
      foaf_surname: Boudon
  - foaf_Person:
      foaf_givenName: Gladys
      foaf_name: Cloarec, Gladys
      foaf_surname: Cloarec
  - foaf_Person:
      foaf_givenName: Ursula
      foaf_name: Abad, Ursula
      foaf_surname: Abad
  - foaf_Person:
      foaf_givenName: Coralie
      foaf_name: Cellier, Coralie
      foaf_surname: Cellier
  - foaf_Person:
      foaf_givenName: Xu
      foaf_name: Chen, Xu
      foaf_surname: Chen
      foaf_workInfoHomepage: http://www.librecat.org/personId=4E5ADCAA-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Benjamin
      foaf_name: Gilles, Benjamin
      foaf_surname: Gilles
  - foaf_Person:
      foaf_givenName: Pascale
      foaf_name: Milani, Pascale
      foaf_surname: Milani
  - foaf_Person:
      foaf_givenName: Jirí
      foaf_name: Friml, Jirí
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  - foaf_Person:
      foaf_givenName: Teva
      foaf_name: Vernoux, Teva
      foaf_surname: Vernoux
  - foaf_Person:
      foaf_givenName: Christophe
      foaf_name: Godin, Christophe
      foaf_surname: Godin
  - foaf_Person:
      foaf_givenName: Olivier
      foaf_name: Hamant, Olivier
      foaf_surname: Hamant
  - foaf_Person:
      foaf_givenName: Jan
      foaf_name: Traas, Jan
      foaf_surname: Traas
  bibo_doi: 10.1016/j.cub.2014.08.036
  bibo_issue: '19'
  bibo_volume: 24
  dct_date: 2014^xs_gYear
  dct_identifier:
  - UT:000342747600031
  dct_language: eng
  dct_publisher: Cell Press@
  dct_title: An auxin-mediated shift toward growth isotropy promotes organ formation
    at the shoot meristem in Arabidopsis@
...