---
res:
  bibo_abstract:
  - Hormone perception and signaling pathways have a fundamental regulatory function
    in the physiological processes of plants. Cytokinins, a class of plant hormones,
    regulate cell division and meristem maintenance. The cytokinin signaling pathway
    is well established in the model plant Arabidopsis thaliana. Several negative
    feedback mechanisms, tightly controlling cytokinin signaling output, have been
    described previously. In this study, we identified a new feedback mechanism executed
    through alternative splicing of the cytokinin receptor AHK4/CRE1. A novel splicing
    variant named CRE1int7 results from seventh intron retention, introducing a premature
    termination codon in the transcript. We showed that CRE1int7 is translated in
    planta into a truncated receptor lacking the C-terminal receiver domain essential
    for signal transduction. CRE1int7 can bind cytokinin but cannot activate the downstream
    cascade. We present a novel negative feedback mechanism of the cytokinin signaling
    pathway, facilitated by a decoy receptor that can inactivate canonical cytokinin
    receptors via dimerization and compete with them for ligand binding. Ensuring
    proper plant growth and development requires precise control of the cytokinin
    signaling pathway at several levels. CRE1int7 represents a so-far unknown mechanism
    for fine-tuning the cytokinin signaling pathway in Arabidopsis.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Michaela
      foaf_name: Králová, Michaela
      foaf_surname: Králová
  - foaf_Person:
      foaf_givenName: Ivona
      foaf_name: Kubalová, Ivona
      foaf_surname: Kubalová
  - foaf_Person:
      foaf_givenName: Jakub
      foaf_name: Hajný, Jakub
      foaf_surname: Hajný
  - foaf_Person:
      foaf_givenName: Karolina
      foaf_name: Kubiasova, Karolina
      foaf_surname: Kubiasova
      foaf_workInfoHomepage: http://www.librecat.org/personId=946011F4-3E71-11EA-860B-C7A73DDC885E
    orcid: 0000-0001-5630-9419
  - foaf_Person:
      foaf_givenName: Karolína
      foaf_name: Vagaská, Karolína
      foaf_surname: Vagaská
  - foaf_Person:
      foaf_givenName: Zengxiang
      foaf_name: Ge, Zengxiang
      foaf_surname: Ge
      foaf_workInfoHomepage: http://www.librecat.org/personId=f43371a3-09ff-11eb-8013-bd0c6a2f6de8
    orcid: 0000-0001-9381-3577
  - foaf_Person:
      foaf_givenName: Michelle C
      foaf_name: Gallei, Michelle C
      foaf_surname: Gallei
      foaf_workInfoHomepage: http://www.librecat.org/personId=35A03822-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-1286-7368
  - foaf_Person:
      foaf_givenName: Hana
      foaf_name: Semerádová, Hana
      foaf_surname: Semerádová
      foaf_workInfoHomepage: http://www.librecat.org/personId=42FE702E-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Anna
      foaf_name: Kuchařová, Anna
      foaf_surname: Kuchařová
  - foaf_Person:
      foaf_givenName: Martin
      foaf_name: Hönig, Martin
      foaf_surname: Hönig
  - foaf_Person:
      foaf_givenName: Aline
      foaf_name: Monzer, Aline
      foaf_surname: Monzer
      foaf_workInfoHomepage: http://www.librecat.org/personId=2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  - foaf_Person:
      foaf_givenName: Martin
      foaf_name: Kovačik, Martin
      foaf_surname: Kovačik
  - foaf_Person:
      foaf_givenName: Jiří
      foaf_name: Friml, Jiří
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  - foaf_Person:
      foaf_givenName: Ondřej
      foaf_name: Novák, Ondřej
      foaf_surname: Novák
  - foaf_Person:
      foaf_givenName: Eva
      foaf_name: Benková, Eva
      foaf_surname: Benková
      foaf_workInfoHomepage: http://www.librecat.org/personId=38F4F166-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8510-9739
  - foaf_Person:
      foaf_givenName: Yoshihisa
      foaf_name: Ikeda, Yoshihisa
      foaf_surname: Ikeda
  - foaf_Person:
      foaf_givenName: David
      foaf_name: Zalabák, David
      foaf_surname: Zalabák
  bibo_doi: 10.1016/j.molp.2024.11.001
  bibo_issue: '12'
  bibo_volume: 17
  dct_date: 2024^xs_gYear
  dct_identifier:
  - UT:001373778300001
  dct_isPartOf:
  - http://id.crossref.org/issn/1674-2052
  dct_language: eng
  dct_publisher: Elsevier@
  dct_title: A decoy receptor derived from alternative splicing fine-tunes cytokinin
    signaling in Arabidopsis@
  fabio_hasPubmedId: '39501563'
...