---
res:
  bibo_abstract:
  - Transcription by RNA polymerase II (Pol II) can be repressed by noncoding RNA,
    including the human RNA Alu. However, the mechanism by which endogenous RNAs repress
    transcription remains unclear. Here we present cryogenic-electron microscopy structures
    of Pol II bound to Alu RNA, which reveal that Alu RNA mimics how DNA and RNA bind
    to Pol II during transcription elongation. Further, we show how distinct domains
    of the general transcription factor TFIIF control repressive activity. Together,
    we reveal how a noncoding RNA can regulate mammalian gene expression.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Katarina
      foaf_name: Tluckova, Katarina
      foaf_surname: Tluckova
      foaf_workInfoHomepage: http://www.librecat.org/personId=4AC7D980-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Beata M
      foaf_name: Kaczmarek, Beata M
      foaf_surname: Kaczmarek
      foaf_workInfoHomepage: http://www.librecat.org/personId=36FA4AFA-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Anita P
      foaf_name: Testa Salmazo, Anita P
      foaf_surname: Testa Salmazo
      foaf_workInfoHomepage: http://www.librecat.org/personId=41F1F098-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Carrie A
      foaf_name: Bernecky, Carrie A
      foaf_surname: Bernecky
      foaf_workInfoHomepage: http://www.librecat.org/personId=2CB9DFE2-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-0893-7036
  bibo_doi: 10.1038/s41594-024-01448-7
  bibo_volume: 32
  dct_date: 2025^xs_gYear
  dct_identifier:
  - UT:001390268000001
  dct_isPartOf:
  - http://id.crossref.org/issn/1545-9993
  - http://id.crossref.org/issn/1545-9985
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: Mechanism of mammalian transcriptional repression by noncoding RNA@
  fabio_hasPubmedId: '39762629'
...