@article{1924,
  abstract     = {Stomata are two-celled valves that control epidermal pores whose spacing optimizes shoot-atmosphere gas exchange. They develop from protodermal cells after unequal divisions followed by an equal division and differentiation. The concentration of the hormone auxin, a master plant developmental regulator, is tightly controlled in time and space, but its role, if any, in stomatal formation is obscure. Here dynamic changes of auxin activity during stomatal development are monitored using auxin input (DII-VENUS) and output (DR5:VENUS) markers by time-lapse imaging. A decrease in auxin levels in the smaller daughter cell after unequal division presages the acquisition of a guard mother cell fate whose equal division produces the two guard cells. Thus, stomatal patterning requires auxin pathway control of stem cell compartment size, as well as auxin depletion that triggers a developmental switch from unequal to equal division.},
  author       = {Le, Jie and Liu, Xuguang and Yang, Kezhen and Chen, Xiaolan and Zhu, Lingling and Wang, Hongzhe and Wang, Ming and Vanneste, Steffen and Morita, Miyo and Tasaka, Masao and Ding, Zhaojun and Friml, Jirí and Beeckman, Tom and Sack, Fred},
  journal      = {Nature Communications},
  publisher    = {Nature Publishing Group},
  title        = {{Auxin transport and activity regulate stomatal patterning and development}},
  doi          = {10.1038/ncomms4090},
  volume       = {5},
  year         = {2014},
}