---
_id: '1924'
abstract:
- lang: eng
  text: Stomata are two-celled valves that control epidermal pores whose spacing optimizes
    shoot-atmosphere gas exchange. They develop from protodermal cells after unequal
    divisions followed by an equal division and differentiation. The concentration
    of the hormone auxin, a master plant developmental regulator, is tightly controlled
    in time and space, but its role, if any, in stomatal formation is obscure. Here
    dynamic changes of auxin activity during stomatal development are monitored using
    auxin input (DII-VENUS) and output (DR5:VENUS) markers by time-lapse imaging.
    A decrease in auxin levels in the smaller daughter cell after unequal division
    presages the acquisition of a guard mother cell fate whose equal division produces
    the two guard cells. Thus, stomatal patterning requires auxin pathway control
    of stem cell compartment size, as well as auxin depletion that triggers a developmental
    switch from unequal to equal division.
article_number: '3090'
article_processing_charge: No
author:
- first_name: Jie
  full_name: Le, Jie
  last_name: Le
- first_name: Xuguang
  full_name: Liu, Xuguang
  last_name: Liu
- first_name: Kezhen
  full_name: Yang, Kezhen
  last_name: Yang
- first_name: Xiaolan
  full_name: Chen, Xiaolan
  last_name: Chen
- first_name: Lingling
  full_name: Zhu, Lingling
  last_name: Zhu
- first_name: Hongzhe
  full_name: Wang, Hongzhe
  last_name: Wang
- first_name: Ming
  full_name: Wang, Ming
  last_name: Wang
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
- first_name: Miyo
  full_name: Morita, Miyo
  last_name: Morita
- first_name: Masao
  full_name: Tasaka, Masao
  last_name: Tasaka
- first_name: Zhaojun
  full_name: Ding, Zhaojun
  last_name: Ding
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Tom
  full_name: Beeckman, Tom
  last_name: Beeckman
- first_name: Fred
  full_name: Sack, Fred
  last_name: Sack
citation:
  ama: Le J, Liu X, Yang K, et al. Auxin transport and activity regulate stomatal
    patterning and development. <i>Nature Communications</i>. 2014;5. doi:<a href="https://doi.org/10.1038/ncomms4090">10.1038/ncomms4090</a>
  apa: Le, J., Liu, X., Yang, K., Chen, X., Zhu, L., Wang, H., … Sack, F. (2014).
    Auxin transport and activity regulate stomatal patterning and development. <i>Nature
    Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/ncomms4090">https://doi.org/10.1038/ncomms4090</a>
  chicago: Le, Jie, Xuguang Liu, Kezhen Yang, Xiaolan Chen, Lingling Zhu, Hongzhe
    Wang, Ming Wang, et al. “Auxin Transport and Activity Regulate Stomatal Patterning
    and Development.” <i>Nature Communications</i>. Nature Publishing Group, 2014.
    <a href="https://doi.org/10.1038/ncomms4090">https://doi.org/10.1038/ncomms4090</a>.
  ieee: J. Le <i>et al.</i>, “Auxin transport and activity regulate stomatal patterning
    and development,” <i>Nature Communications</i>, vol. 5. Nature Publishing Group,
    2014.
  ista: Le J, Liu X, Yang K, Chen X, Zhu L, Wang H, Wang M, Vanneste S, Morita M,
    Tasaka M, Ding Z, Friml J, Beeckman T, Sack F. 2014. Auxin transport and activity
    regulate stomatal patterning and development. Nature Communications. 5, 3090.
  mla: Le, Jie, et al. “Auxin Transport and Activity Regulate Stomatal Patterning
    and Development.” <i>Nature Communications</i>, vol. 5, 3090, Nature Publishing
    Group, 2014, doi:<a href="https://doi.org/10.1038/ncomms4090">10.1038/ncomms4090</a>.
  short: J. Le, X. Liu, K. Yang, X. Chen, L. Zhu, H. Wang, M. Wang, S. Vanneste, M.
    Morita, M. Tasaka, Z. Ding, J. Friml, T. Beeckman, F. Sack, Nature Communications
    5 (2014).
date_created: 2018-12-11T11:54:44Z
date_published: 2014-01-27T00:00:00Z
date_updated: 2025-09-29T12:15:23Z
day: '27'
department:
- _id: JiFr
doi: 10.1038/ncomms4090
external_id:
  isi:
  - '000331084200032'
intvolume: '         5'
isi: 1
language:
- iso: eng
month: '01'
oa_version: None
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5170'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin transport and activity regulate stomatal patterning and development
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 5
year: '2014'
...