---
res:
  bibo_abstract:
  - "Plant growth and development rely significantly on phytohormones, with auxin
    serving as a master regulator, orchestrating processes from embryogenesis to organogenesis,
    vascular patterning, and environmental adaptation. Since its conceptual proposition
    by Charles Darwin in 1880 as an endogenous chemical signal influencing phototropism
    in grass, auxin has captivated scientists seeking to understand how such a small
    molecule exerts a profound influence on plant development.\r\nOne particularly
    fascinating aspect of auxin function is its ability to self-organize its transport.
    Through a feedback mechanism between auxin perception and directional transport—primarily
    mediated by PIN auxin transporters—auxin establishes narrow transport channels.
    This phenomenon, known as auxin canalization, is fundamental to vascular formation,
    regeneration, and other key developmental processes. Despite advances in our understanding,
    driven by experimental studies and computational models, auxin canalization remains
    an enigma, with many unanswered questions.\r\nLike other hormones, auxin functions
    through intricate signaling pathways. It operates through at least two distinct
    signaling mechanisms: the well-characterized canonical pathway and the less understood
    non-canonical pathway. While significant progress has been made in elucidating
    the canonical pathway, the non-canonical mechanisms remain less defined and require
    further investigation.\r\nIn this study, we revisit the non-canonical auxin signaling
    pathway mediated by the cell-surface complex Auxin Binding Protein 1-Transmembrane
    Kinase 1 (ABP1-TMK1), with a particular focus on its downstream phosphorylation
    events. We reveal that this auxin-mediated phosphorylation is conserved across
    the green lineage, underscoring its fundamental role in plant development. We
    explore key phosphorylation targets, particularly PIN2, which is essential for
    root gravitropism. To further understand TMK1’s role in diverse developmental
    processes, we identified and investigated its interactors as potential co-receptors
    or regulatory components within its signaling network.\r\nGiven the previously
    established role of ABP1-TMK1 in auxin canalization, we sought to further investigate
    this process and identified several TMK1 interactors also involved in this intricate
    mechanism.\r\nThese findings provide new insights into the complex regulation
    of auxin canalization, highlighting a broader and more interconnected signaling
    framework than previously understood.@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Aline
      foaf_name: Monzer, Aline
      foaf_surname: Monzer
      foaf_workInfoHomepage: http://www.librecat.org/personId=2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  bibo_doi: 10.15479/AT-ISTA-19395
  dct_date: 2025^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2663-337X
  dct_language: eng
  dct_publisher: Institute of Science and Technology Austria@
  dct_title: 'Cell-Surface Auxin Signaling: Linking molecular pathways to plant development@'
...