---
res:
  bibo_abstract:
  - Auxin and its PIN-FORMED (PIN) exporters are essential for tissue repair and regeneration
    in flowering plants. To gain insight into the evolution of this mechanism, we
    investigated their roles in leaves excised from Physcomitrium patens, a bryophyte
    known for its remarkable cell reprogramming capacity. We used various approaches
    to manipulate auxin levels, including exogenous application, pharmacological manipulations,
    and auxin biosynthesis mutants. We observed no significant effect on the rate
    of cell reprogramming. Rather, our analysis of auxin dynamics revealed a decrease
    in auxin levels upon excision, which was followed by a local increase before the
    reprogramming process began. Mutant analysis revealed that PpPINs are required
    for effective cell reprogramming, and endogenously expressed PpPINA-GFP accumulates
    polarly at sites that will develop into future filamentous stem cells. In addition,
    hyperpolarized PpPINA variants carrying mutated phosphorylation sites showed a
    marked delay in reprogramming, whereas endogenous or nonpolar versions do not
    have this effect. These results underscore that both the levels and the polarity
    of PpPINA are important for efficient cell reprogramming. Overall, these findings
    highlight the pivotal role of PIN polarity in plant regeneration. Furthermore,
    they suggest that understanding polarity mechanisms could have broader implications
    for improving regenerative processes across various plant species.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Han
      foaf_name: Tang, Han
      foaf_surname: Tang
      foaf_workInfoHomepage: http://www.librecat.org/personId=19BDF720-25A0-11EA-AC6E-928F3DDC885E
    orcid: 0000-0001-6152-6637
  - foaf_Person:
      foaf_givenName: L
      foaf_name: Chen, L
      foaf_surname: Chen
  - foaf_Person:
      foaf_givenName: Jiří
      foaf_name: Friml, Jiří
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  bibo_doi: 10.1093/pcp/pcaf008
  dct_date: 2025^xs_gYear
  dct_identifier:
  - UT:001436802900001
  dct_isPartOf:
  - http://id.crossref.org/issn/0032-0781
  - http://id.crossref.org/issn/1471-9053
  dct_language: eng
  dct_publisher: Oxford University Press@
  dct_title: Auxin fluctuation and PIN polarization in moss leaf cell reprogramming.@
  fabio_hasPubmedId: '39829340'
...