{"ddc":["570"],"author":[{"full_name":"Bollmann, Lars","last_name":"Bollmann","id":"47AD3038-F248-11E8-B48F-1D18A9856A87","first_name":"Lars"},{"full_name":"Baracskay, Peter","id":"361CC00E-F248-11E8-B48F-1D18A9856A87","last_name":"Baracskay","first_name":"Peter"},{"id":"39AF1E74-F248-11E8-B48F-1D18A9856A87","last_name":"Stella","first_name":"Federico","orcid":"0000-0001-9439-3148","full_name":"Stella, Federico"},{"full_name":"Csicsvari, Jozsef L","orcid":"0000-0002-5193-4036","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari"}],"publication_status":"inpress","publisher":"Elsevier","year":"2025","doi":"10.1016/j.neuron.2025.02.025","citation":{"ista":"Bollmann L, Baracskay P, Stella F, Csicsvari JL. Sleep stages antagonistically modulate reactivation drift. Neuron.","ama":"Bollmann L, Baracskay P, Stella F, Csicsvari JL. Sleep stages antagonistically modulate reactivation drift. Neuron. doi:10.1016/j.neuron.2025.02.025","mla":"Bollmann, Lars, et al. “Sleep Stages Antagonistically Modulate Reactivation Drift.” Neuron, Elsevier, doi:10.1016/j.neuron.2025.02.025.","short":"L. Bollmann, P. Baracskay, F. Stella, J.L. Csicsvari, Neuron (n.d.).","ieee":"L. Bollmann, P. Baracskay, F. Stella, and J. L. Csicsvari, “Sleep stages antagonistically modulate reactivation drift,” Neuron. Elsevier.","chicago":"Bollmann, Lars, Peter Baracskay, Federico Stella, and Jozsef L Csicsvari. “Sleep Stages Antagonistically Modulate Reactivation Drift.” Neuron. Elsevier, n.d. https://doi.org/10.1016/j.neuron.2025.02.025.","apa":"Bollmann, L., Baracskay, P., Stella, F., & Csicsvari, J. L. (n.d.). Sleep stages antagonistically modulate reactivation drift. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2025.02.025"},"publication":"Neuron","oa":1,"OA_type":"hybrid","has_accepted_license":"1","date_updated":"2025-05-14T11:39:26Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","language":[{"iso":"eng"}],"date_created":"2025-04-06T22:01:32Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.neuron.2025.02.025"}],"oa_version":"Published Version","department":[{"_id":"JoCs"}],"abstract":[{"text":"Hippocampal reactivation of waking neuronal assemblies in sleep is a key initial step of systems consolidation. Nevertheless, it is unclear whether reactivated assemblies are static or whether they reorganize gradually over prolonged sleep. We tracked reactivated CA1 assembly patterns over ∼20 h of sleep/rest periods and related them to assemblies seen before or after in a spatial learning paradigm using rats. We found that reactivated assembly patterns were gradually transformed and started to resemble those seen in the subsequent recall session. Periods of rapid eye movement (REM) sleep and non-REM (NREM) had antagonistic roles: whereas NREM accelerated the assembly drift, REM countered it. Moreover, only a subset of rate-changing pyramidal cells contributed to the drift, whereas stable-firing-rate cells maintained unaltered reactivation patterns. Our data suggest that prolonged sleep promotes the spontaneous reorganization of spatial assemblies, which can contribute to daily cognitive map changes or encoding new learning situations.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","month":"03","day":"24","license":"https://creativecommons.org/licenses/by/4.0/","title":"Sleep stages antagonistically modulate reactivation drift","status":"public","type":"journal_article","corr_author":"1","_id":"19506","date_published":"2025-03-24T00:00:00Z","publication_identifier":{"issn":["0896-6273"],"eissn":["1097-4199"]},"acknowledgement":"We thank Andrea Cumpelik, Lisa Genzel, and Freya Ólafsdóttir for comments on an earlier version of the manuscript. This work was supported by the European Research Council (281511) and Austrian Science Fund (FWF I3713).","ec_funded":1,"project":[{"name":"Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex","_id":"257A4776-B435-11E9-9278-68D0E5697425","grant_number":"281511","call_identifier":"FP7"},{"call_identifier":"FWF","grant_number":"I 3713-B27","_id":"2654F984-B435-11E9-9278-68D0E5697425","name":"Interneuro plasticity during spatial learning"}],"OA_place":"publisher","article_processing_charge":"Yes (via OA deal)","quality_controlled":"1"}