---
res:
  bibo_abstract:
  - In animal and plant cells, mitotic chromatin locally generates microtubules that
    self-organize into a mitotic spindle, and its dimensions and bipolar symmetry
    are essential for accurate chromosome segregation. By immobilizing microscopic
    chromatin-coated beads on slide surfaces using a microprinting technique, we have
    examined the effect of chromatin on the dimensions and symmetry of spindles in
    Xenopus laevis cytoplasmic extracts. While circular spots with diameters around
    14-18 μm trigger bipolar spindle formation, larger spots generate an incorrect
    number of poles. We also examined lines of chromatin with various dimensions.
    Their length determined the number of poles that formed, with a 6 × 18 μm rectangular
    patch generating normal spindle morphology. Around longer lines, multiple poles
    formed and the structures were disorganized. While lines thinner than 10 μm generated
    symmetric structures, thicker lines induced the formation of asymmetric structures
    where all microtubules are on the same side of the line. Our results show that
    chromatin defines spindle shape and orientation. For a video summary of this article,
    see the PaperFlick file available with the online Supplemental Data.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Ana
      foaf_name: Dinarina, Ana
      foaf_surname: Dinarina
  - foaf_Person:
      foaf_givenName: Céline
      foaf_name: Pugieux, Céline
      foaf_surname: Pugieux
  - foaf_Person:
      foaf_givenName: Maria
      foaf_name: Corral, Maria M
      foaf_surname: Corral
  - foaf_Person:
      foaf_givenName: Martin
      foaf_name: Martin Loose
      foaf_surname: Loose
      foaf_workInfoHomepage: http://www.librecat.org/personId=462D4284-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-7309-9724
  - foaf_Person:
      foaf_givenName: Joachim
      foaf_name: Spatz, Joachim P
      foaf_surname: Spatz
  - foaf_Person:
      foaf_givenName: Éric
      foaf_name: Karsenti, Éric
      foaf_surname: Karsenti
  - foaf_Person:
      foaf_givenName: François
      foaf_name: Nédélec, François J
      foaf_surname: Nédélec
  bibo_doi: 10.1016/j.cell.2009.05.027
  bibo_issue: '3'
  bibo_volume: 138
  dct_date: 2009^xs_gYear
  dct_publisher: Cell Press@
  dct_title: Chromatin shapes the mitotic spindle@
...