[{"day":"01","date_published":"2025-12-01T00:00:00Z","ddc":["570"],"publication_identifier":{"eissn":["2214-5753"],"issn":["2214-5745"]},"date_created":"2025-08-17T22:01:35Z","corr_author":"1","author":[{"full_name":"Toups, Melissa A","first_name":"Melissa A","last_name":"Toups","orcid":"0000-0002-9752-7380","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Beatriz","full_name":"Vicoso, Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4579-8306","last_name":"Vicoso"}],"publication":"Current Opinion in Insect Science","license":"https://creativecommons.org/licenses/by/4.0/","PlanS_conform":"1","publication_status":"published","OA_place":"publisher","language":[{"iso":"eng"}],"citation":{"chicago":"Toups, Melissa A, and Beatriz Vicoso. “Insect Sex Chromosome Evolution: Conservation, Turnover, and Mechanisms of Dosage Compensation.” <i>Current Opinion in Insect Science</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.cois.2025.101411\">https://doi.org/10.1016/j.cois.2025.101411</a>.","short":"M.A. Toups, B. Vicoso, Current Opinion in Insect Science 72 (2025).","apa":"Toups, M. A., &#38; Vicoso, B. (2025). Insect sex chromosome evolution: Conservation, turnover, and mechanisms of dosage compensation. <i>Current Opinion in Insect Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cois.2025.101411\">https://doi.org/10.1016/j.cois.2025.101411</a>","ieee":"M. A. Toups and B. Vicoso, “Insect sex chromosome evolution: Conservation, turnover, and mechanisms of dosage compensation,” <i>Current Opinion in Insect Science</i>, vol. 72. Elsevier, 2025.","mla":"Toups, Melissa A., and Beatriz Vicoso. “Insect Sex Chromosome Evolution: Conservation, Turnover, and Mechanisms of Dosage Compensation.” <i>Current Opinion in Insect Science</i>, vol. 72, 101411, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.cois.2025.101411\">10.1016/j.cois.2025.101411</a>.","ista":"Toups MA, Vicoso B. 2025. Insect sex chromosome evolution: Conservation, turnover, and mechanisms of dosage compensation. Current Opinion in Insect Science. 72, 101411.","ama":"Toups MA, Vicoso B. Insect sex chromosome evolution: Conservation, turnover, and mechanisms of dosage compensation. <i>Current Opinion in Insect Science</i>. 2025;72. doi:<a href=\"https://doi.org/10.1016/j.cois.2025.101411\">10.1016/j.cois.2025.101411</a>"},"article_processing_charge":"Yes (via OA deal)","status":"public","type":"journal_article","doi":"10.1016/j.cois.2025.101411","scopus_import":"1","article_number":"101411","intvolume":"        72","article_type":"review","has_accepted_license":"1","month":"12","abstract":[{"text":"Sex chromosomes have evolved many times throughout the tree of life, and understanding what has shaped their unusual morphological, sequence, and regulatory features has been a long-standing goal. Most early insights into insect sex chromosome biology came from a few model species, such as the fruit fly Drosophila melanogaster, which limited broad-scale evolutionary inferences. More recently, extensive comparative genomics studies have uncovered several unexpected patterns, which we highlight in this review. First, we describe the conservation of the ancestral X chromosome over 450 million years but also its recurrent turnover (i.e. its reversal to an autosome when a new X chromosome arose) in at least one order. We then summarize classical and more recent findings on how insects modulate the expression of X-linked genes following the degradation of the Y chromosome and how the diverse mechanisms of dosage compensation identified may elucidate important principles of sex chromosome regulatory evolution.","lang":"eng"}],"file":[{"file_id":"20917","date_updated":"2025-12-30T13:14:20Z","relation":"main_file","success":1,"date_created":"2025-12-30T13:14:20Z","file_size":897079,"checksum":"262640abc34277686b56eb60102976f6","file_name":"2025_CurrOpinionInsectScience_Toups.pdf","creator":"dernst","content_type":"application/pdf","access_level":"open_access"}],"OA_type":"hybrid","project":[{"grant_number":"PAT 8748323","name":"Sex chromosomes in evolution and development","_id":"8ed82125-16d5-11f0-9cad-fbcae312235b"}],"oa":1,"volume":72,"_id":"20182","title":"Insect sex chromosome evolution: Conservation, turnover, and mechanisms of dosage compensation","department":[{"_id":"BeVi"}],"date_updated":"2025-12-30T13:14:38Z","external_id":{"isi":["001582424100001"]},"oa_version":"Published Version","acknowledgement":"This work was supported by an Austrian Research Fund (FWF) grant to B.V. (PAT 8748323) and by the Louisiana Board of Regents Research Competitiveness Subprogram (LEQSF(2025-28)-RD-A-20) to MAT.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","isi":1,"publisher":"Elsevier","file_date_updated":"2025-12-30T13:14:20Z","quality_controlled":"1"}]