---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20349'
abstract:
- lang: eng
  text: Oogenesis – the formation and development of an oocyte – is fundamental to
    reproduction and embryonic development. Due to its accessibility to genetic manipulations
    and the ability to culture and experimentally manipulate oocytes ex vivo, zebrafish
    has emerged as a powerful vertebrate model system for studying oogenesis. In this
    review, we provide a comprehensive overview of zebrafish oogenesis, from early
    germ cell formation to oocyte maturation and fertilization. We discuss recent
    advances in uncovering the molecular and cellular mechanisms driving this complex
    process and highlight key knowledge gaps that remain to be addressed.
acknowledgement: We thank Carolina Camelo for making schematics for this review.
article_number: '103650'
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Laura
  full_name: Hofmann, Laura
  id: b88d43f2-dc74-11ea-a0a7-e41b7912e031
  last_name: Hofmann
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: 'Hofmann L, Heisenberg C-PJ. Decoding zebrafish oogenesis: From primordial
    germ cell development to fertilization. <i>Seminars in Cell and Developmental
    Biology</i>. 2025;175. doi:<a href="https://doi.org/10.1016/j.semcdb.2025.103650">10.1016/j.semcdb.2025.103650</a>'
  apa: 'Hofmann, L., &#38; Heisenberg, C.-P. J. (2025). Decoding zebrafish oogenesis:
    From primordial germ cell development to fertilization. <i>Seminars in Cell and
    Developmental Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.semcdb.2025.103650">https://doi.org/10.1016/j.semcdb.2025.103650</a>'
  chicago: 'Hofmann, Laura, and Carl-Philipp J Heisenberg. “Decoding Zebrafish Oogenesis:
    From Primordial Germ Cell Development to Fertilization.” <i>Seminars in Cell and
    Developmental Biology</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.semcdb.2025.103650">https://doi.org/10.1016/j.semcdb.2025.103650</a>.'
  ieee: 'L. Hofmann and C.-P. J. Heisenberg, “Decoding zebrafish oogenesis: From primordial
    germ cell development to fertilization,” <i>Seminars in Cell and Developmental
    Biology</i>, vol. 175. Elsevier, 2025.'
  ista: 'Hofmann L, Heisenberg C-PJ. 2025. Decoding zebrafish oogenesis: From primordial
    germ cell development to fertilization. Seminars in Cell and Developmental Biology.
    175, 103650.'
  mla: 'Hofmann, Laura, and Carl-Philipp J. Heisenberg. “Decoding Zebrafish Oogenesis:
    From Primordial Germ Cell Development to Fertilization.” <i>Seminars in Cell and
    Developmental Biology</i>, vol. 175, 103650, Elsevier, 2025, doi:<a href="https://doi.org/10.1016/j.semcdb.2025.103650">10.1016/j.semcdb.2025.103650</a>.'
  short: L. Hofmann, C.-P.J. Heisenberg, Seminars in Cell and Developmental Biology
    175 (2025).
corr_author: '1'
date_created: 2025-09-14T22:01:32Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2025-12-30T10:21:13Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1016/j.semcdb.2025.103650
external_id:
  isi:
  - '001567260100001'
  pmid:
  - '40913907'
file:
- access_level: open_access
  checksum: 80ea6cbb004853bb1e87db3422a74aca
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-30T10:21:00Z
  date_updated: 2025-12-30T10:21:00Z
  file_id: '20914'
  file_name: 2025_SemCellDevBiology_Hofmann.pdf
  file_size: 2778561
  relation: main_file
  success: 1
file_date_updated: 2025-12-30T10:21:00Z
fulldoi: https://doi.org/10.1016/j.semcdb.2025.103650
has_accepted_license: '1'
intvolume: '       175'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Seminars in Cell and Developmental Biology
publication_identifier:
  eissn:
  - 1096-3634
  issn:
  - 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Decoding zebrafish oogenesis: From primordial germ cell development to fertilization'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 175
year: '2025'
...