{"date_created":"2025-11-23T23:01:38Z","OA_type":"hybrid","article_processing_charge":"Yes (in subscription journal)","publication":"Proceedings of the National Academy of Sciences of the United States of America","issue":"46","_id":"20663","doi":"10.1073/pnas.2506400122","year":"2025","language":[{"iso":"eng"}],"publisher":"National Academy of Sciences","oa_version":"Published Version","article_type":"original","page":"e2506400122","date_updated":"2025-11-24T09:52:40Z","acknowledgement":"This study was funded by the BBSRC (grant no. BB/N010124/1) and Leverhulme Foundation (grant no. RPG-2018-137) to M.D.B. and S.K., a Fully Funded International Research Scholarship awarded to K.S.-F., and by NASA (grant no. 80NSSC21K0585) to C.W.","quality_controlled":"1","day":"18","pmid":1,"author":[{"first_name":"Suruchi","last_name":"Roychoudhry","full_name":"Roychoudhry, Suruchi"},{"full_name":"Sageman-Furnas, Katelyn","last_name":"Sageman-Furnas","first_name":"Katelyn"},{"first_name":"Harry J.","full_name":"Taylor, Harry J.","last_name":"Taylor"},{"first_name":"Iftekhar","last_name":"Showpnil","full_name":"Showpnil, Iftekhar"},{"first_name":"Chris","last_name":"Wolverton","full_name":"Wolverton, Chris"},{"orcid":"0000-0002-8302-7596","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","last_name":"Friml"},{"first_name":"Marta Del","last_name":"Bianco","full_name":"Bianco, Marta Del"},{"last_name":"Kepinski","full_name":"Kepinski, Stefan","first_name":"Stefan"}],"abstract":[{"lang":"eng","text":"Gravitropism, the patterning of postembryonic growth in relation to the gravity vector, allows plants to optimize the use of limited and nonhomogenous resources in their immediate environment. Since the current model of root gravitropism has not been able to integrate all aspects of the response (perception, response, and behavior), research on gravitropism has been dominated by different theories attempting to conceptualize each aspect individually. In this work, we sought to reevaluate all the main components of the root graviresponse through the lens of angle dependence. We show angle dependence in Cholodny–Went-based auxin asymmetry and growth response, which we tracked back to angle-dependent variation in PIN asymmetry and statolith sedimentation in the columella. Thanks to this approach, we were able to suggest distinct roles for PINs and columella cell tiers, and a potential function for auxin vertical flux through the columella. Our findings provide a unifying framework to further explore the mechanisms that regulate angle-dependent gravitropic response, with major implications of time-dependent features of root graviresponse."}],"has_accepted_license":"1","title":"Angle dependence as a unifying feature of root graviresponse modules","month":"11","publication_identifier":{"eissn":["1091-6490"]},"citation":{"ama":"Roychoudhry S, Sageman-Furnas K, Taylor HJ, et al. Angle dependence as a unifying feature of root graviresponse modules. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2025;122(46):e2506400122. doi:<a href=\"https://doi.org/10.1073/pnas.2506400122\">10.1073/pnas.2506400122</a>","ieee":"S. Roychoudhry <i>et al.</i>, “Angle dependence as a unifying feature of root graviresponse modules,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 122, no. 46. National Academy of Sciences, p. e2506400122, 2025.","ista":"Roychoudhry S, Sageman-Furnas K, Taylor HJ, Showpnil I, Wolverton C, Friml J, Bianco MD, Kepinski S. 2025. Angle dependence as a unifying feature of root graviresponse modules. Proceedings of the National Academy of Sciences of the United States of America. 122(46), e2506400122.","apa":"Roychoudhry, S., Sageman-Furnas, K., Taylor, H. J., Showpnil, I., Wolverton, C., Friml, J., … Kepinski, S. (2025). Angle dependence as a unifying feature of root graviresponse modules. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2506400122\">https://doi.org/10.1073/pnas.2506400122</a>","short":"S. Roychoudhry, K. Sageman-Furnas, H.J. Taylor, I. Showpnil, C. Wolverton, J. Friml, M.D. Bianco, S. Kepinski, Proceedings of the National Academy of Sciences of the United States of America 122 (2025) e2506400122.","chicago":"Roychoudhry, Suruchi, Katelyn Sageman-Furnas, Harry J. Taylor, Iftekhar Showpnil, Chris Wolverton, Jiří Friml, Marta Del Bianco, and Stefan Kepinski. “Angle Dependence as a Unifying Feature of Root Graviresponse Modules.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2506400122\">https://doi.org/10.1073/pnas.2506400122</a>.","mla":"Roychoudhry, Suruchi, et al. “Angle Dependence as a Unifying Feature of Root Graviresponse Modules.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 122, no. 46, National Academy of Sciences, 2025, p. e2506400122, doi:<a href=\"https://doi.org/10.1073/pnas.2506400122\">10.1073/pnas.2506400122</a>."},"file":[{"success":1,"file_size":1394055,"file_name":"2025_PNAS_Roychoudhry.pdf","creator":"dernst","file_id":"20676","content_type":"application/pdf","relation":"main_file","access_level":"open_access","date_created":"2025-11-24T09:48:44Z","date_updated":"2025-11-24T09:48:44Z","checksum":"5e1c37dddc5db8fbd0128db4a54c4f6b"}],"ddc":["580"],"OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","scopus_import":"1","status":"public","intvolume":"       122","PlanS_conform":"1","oa":1,"external_id":{"pmid":["41218119"]},"file_date_updated":"2025-11-24T09:48:44Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_published":"2025-11-18T00:00:00Z","department":[{"_id":"JiFr"}],"volume":122,"publication_status":"published"}