---
_id: '2071'
abstract:
- lang: eng
  text: The X or Z chromosome has several characteristics that distinguish it from
    the autosomes, namely hemizygosity in the heterogametic sex, and a potentially
    different effective population size, both of which may influence the rate and
    nature of evolution. In particular, there may be an accelerated rate of adaptive
    change for X-linked compared to autosomal coding sequences, often referred to
    as the Faster-X effect. Empirical studies have indicated that the strength of
    Faster-X evolution varies among different species, and theoretical treatments
    have shown that demography and mating system can substantially affect the degree
    of Faster-X evolution. Here we integrate genomic data on Faster-X evolution from
    a variety of animals with the demographic factors, mating system, and sex chromosome
    regulatory characteristics that may influence it. Our results suggest that differences
    in effective population size and mechanisms of dosage compensation may influence
    the perceived extent of Faster-X evolution, and help to explain several clade-specific
    patterns that we observe.
acknowledgement: We gratefully acknowledge funding from the Royal Society (to JEM)
author:
- first_name: Judith
  full_name: Mank, Judith E
  last_name: Mank
- first_name: Beatriz
  full_name: Beatriz Vicoso
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- first_name: Sofia
  full_name: Berlin, Sofia
  last_name: Berlin
- first_name: Brian
  full_name: Charlesworth, Brian
  last_name: Charlesworth
citation:
  ama: 'Mank J, Vicoso B, Berlin S, Charlesworth B. Effective population size and
    the Faster-X effect: Empirical results and their interpretation. <i>Evolution</i>.
    2010;64(3):663-674. doi:<a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">10.1111/j.1558-5646.2009.00853.x</a>'
  apa: 'Mank, J., Vicoso, B., Berlin, S., &#38; Charlesworth, B. (2010). Effective
    population size and the Faster-X effect: Empirical results and their interpretation.
    <i>Evolution</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">https://doi.org/10.1111/j.1558-5646.2009.00853.x</a>'
  chicago: 'Mank, Judith, Beatriz Vicoso, Sofia Berlin, and Brian Charlesworth. “Effective
    Population Size and the Faster-X Effect: Empirical Results and Their Interpretation.”
    <i>Evolution</i>. Wiley-Blackwell, 2010. <a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">https://doi.org/10.1111/j.1558-5646.2009.00853.x</a>.'
  ieee: 'J. Mank, B. Vicoso, S. Berlin, and B. Charlesworth, “Effective population
    size and the Faster-X effect: Empirical results and their interpretation,” <i>Evolution</i>,
    vol. 64, no. 3. Wiley-Blackwell, pp. 663–674, 2010.'
  ista: 'Mank J, Vicoso B, Berlin S, Charlesworth B. 2010. Effective population size
    and the Faster-X effect: Empirical results and their interpretation. Evolution.
    64(3), 663–674.'
  mla: 'Mank, Judith, et al. “Effective Population Size and the Faster-X Effect: Empirical
    Results and Their Interpretation.” <i>Evolution</i>, vol. 64, no. 3, Wiley-Blackwell,
    2010, pp. 663–74, doi:<a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">10.1111/j.1558-5646.2009.00853.x</a>.'
  short: J. Mank, B. Vicoso, S. Berlin, B. Charlesworth, Evolution 64 (2010) 663–674.
date_created: 2018-12-11T11:55:32Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T06:55:07Z
day: '01'
doi: 10.1111/j.1558-5646.2009.00853.x
extern: 1
intvolume: '        64'
issue: '3'
month: '03'
page: 663 - 674
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4967'
quality_controlled: 0
status: public
title: 'Effective population size and the Faster-X effect: Empirical results and their
  interpretation'
type: journal_article
volume: 64
year: '2010'
...