A cascade Suzuki–Miyaura cross-coupling between two non-symmetrical coupling partners gave rise to 9,10-dihydrophenanthrenes with full site-selectivity. The choice of base was critical to facilitate the challenging coupling of the secondary boronate group.
"}],"_id":"20765","language":[{"iso":"eng"}],"title":"A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls","citation":{"mla":"Willems, Suzanne, et al. “A Site-Selective and Stereospecific Cascade Suzuki–Miyaura Annulation of Alkyl 1,2-Bisboronic Esters and 2,2′-Dihalo 1,1′-Biaryls.” Chemical Communications, vol. 57, no. 32, Royal Society of Chemistry, 2021, pp. 3909–12, doi:10.1039/d1cc00648g.","ieee":"S. Willems, G. Toupalas, J. Reisenbauer, and B. Morandi, “A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls,” Chemical Communications, vol. 57, no. 32. Royal Society of Chemistry, pp. 3909–3912, 2021.","ista":"Willems S, Toupalas G, Reisenbauer J, Morandi B. 2021. A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls. Chemical Communications. 57(32), 3909–3912.","short":"S. Willems, G. Toupalas, J. Reisenbauer, B. Morandi, Chemical Communications 57 (2021) 3909–3912.","ama":"Willems S, Toupalas G, Reisenbauer J, Morandi B. A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls. Chemical Communications. 2021;57(32):3909-3912. doi:10.1039/d1cc00648g","apa":"Willems, S., Toupalas, G., Reisenbauer, J., & Morandi, B. (2021). A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls. Chemical Communications. Royal Society of Chemistry. https://doi.org/10.1039/d1cc00648g","chicago":"Willems, Suzanne, Georgios Toupalas, Julia Reisenbauer, and Bill Morandi. “A Site-Selective and Stereospecific Cascade Suzuki–Miyaura Annulation of Alkyl 1,2-Bisboronic Esters and 2,2′-Dihalo 1,1′-Biaryls.” Chemical Communications. Royal Society of Chemistry, 2021. https://doi.org/10.1039/d1cc00648g."},"oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 3.0 Unported (CC BY 3.0)","legal_code_url":"https://creativecommons.org/licenses/by/3.0/legalcode","image":"/images/cc_by.png","short":"CC BY (3.0)"},"date_published":"2021-03-15T00:00:00Z","type":"journal_article","issue":"32","page":"3909-3912","extern":"1","OA_type":"hybrid","ddc":["540"],"main_file_link":[{"open_access":"1","url":"DOI\thttps://doi.org/10.1039/D1CC00648G"}],"article_processing_charge":"No","status":"public","license":"https://creativecommons.org/licenses/by/3.0/","has_accepted_license":"1","date_updated":"2025-12-16T12:06:53Z","volume":57,"publication":"Chemical Communications","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"15","external_id":{"pmid":["33871510"]},"OA_place":"publisher","year":"2021","month":"03","author":[{"first_name":"Suzanne","full_name":"Willems, Suzanne","last_name":"Willems"},{"full_name":"Toupalas, Georgios","first_name":"Georgios","last_name":"Toupalas"},{"last_name":"Reisenbauer","first_name":"Julia","full_name":"Reisenbauer, Julia","id":"51d862e9-36ee-11f0-86d3-8534c85a5496"},{"last_name":"Morandi","first_name":"Bill","full_name":"Morandi, Bill"}]}