@article{20969,
  abstract     = {The diastereoselective assembly of achiral constituents through a single spontaneous process into complex covalent architectures bearing multiple stereogenic elements still remains a challenge for synthetic chemists. Here, we show that such an extreme level of control can be achieved by implementing stereo-electronic information on synthetic organic building blocks and templates and that non-directional interactions (i.e., electrostatic and steric interactions) can transfer this information to deliver, after self-assembly, high-molecular weight macrocyclic species carrying up to 16 stereogenic elements. Beyond the field of supramolecular chemistry, this proof of concept should stimulate the on-demand production of highly structured polyfunctional architectures.},
  author       = {Zhang, Yuan and Ourri, Benjamin and Skowron, Pierre-Thomas and Jeamet, Emeric and Chetot, Titouan and Duchamp, Christian and Belenguer, Ana M. and Vanthuyne, Nicolas and Cala, Olivier and Dumont, Elise and Mandal, Pradeep K and Huc, Ivan and Perret, Florent and Vial, Laurent and Leclaire, Julien},
  issn         = {2041-6539},
  journal      = {Chemical Science},
  number       = {26},
  pages        = {7126--7135},
  publisher    = {Royal Society of Chemistry},
  title        = {{Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions}},
  doi          = {10.1039/d3sc01235b},
  volume       = {14},
  year         = {2023},
}