[{"OA_place":"publisher","page":"7126-7135","oa":1,"volume":14,"quality_controlled":"1","external_id":{"pmid":["37416699"]},"publication_identifier":{"issn":["2041-6520"],"eissn":["2041-6539"]},"month":"05","scopus_import":"1","title":"Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions","publication":"Chemical Science","_id":"20969","type":"journal_article","license":"https://creativecommons.org/licenses/by-nc/3.0/","tmp":{"name":"Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/3.0/legalcode","short":"CC BY-NC (3.0)"},"date_updated":"2026-01-20T07:04:16Z","DOAJ_listed":"1","day":"24","date_created":"2026-01-11T14:38:38Z","issue":"26","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","abstract":[{"lang":"eng","text":"The diastereoselective assembly of achiral constituents through a single spontaneous process into complex covalent architectures bearing multiple stereogenic elements still remains a challenge for synthetic chemists. Here, we show that such an extreme level of control can be achieved by implementing stereo-electronic information on synthetic organic building blocks and templates and that non-directional interactions (i.e., electrostatic and steric interactions) can transfer this information to deliver, after self-assembly, high-molecular weight macrocyclic species carrying up to 16 stereogenic elements. Beyond the field of supramolecular chemistry, this proof of concept should stimulate the on-demand production of highly structured polyfunctional architectures."}],"ddc":["540"],"doi":"10.1039/d3sc01235b","oa_version":"Published Version","article_processing_charge":"Yes","publisher":"Royal Society of Chemistry","language":[{"iso":"eng"}],"has_accepted_license":"1","status":"public","intvolume":"        14","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1039/D3SC01235B"}],"author":[{"full_name":"Zhang, Yuan","last_name":"Zhang","first_name":"Yuan"},{"last_name":"Ourri","full_name":"Ourri, Benjamin","first_name":"Benjamin"},{"first_name":"Pierre-Thomas","full_name":"Skowron, Pierre-Thomas","last_name":"Skowron"},{"first_name":"Emeric","last_name":"Jeamet","full_name":"Jeamet, Emeric"},{"first_name":"Titouan","last_name":"Chetot","full_name":"Chetot, Titouan"},{"last_name":"Duchamp","full_name":"Duchamp, Christian","first_name":"Christian"},{"full_name":"Belenguer, Ana M.","last_name":"Belenguer","first_name":"Ana M."},{"first_name":"Nicolas","last_name":"Vanthuyne","full_name":"Vanthuyne, Nicolas"},{"last_name":"Cala","full_name":"Cala, Olivier","first_name":"Olivier"},{"last_name":"Dumont","full_name":"Dumont, Elise","first_name":"Elise"},{"id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","last_name":"Mandal","full_name":"Mandal, Pradeep K","first_name":"Pradeep K","orcid":"0000-0001-5996-956X"},{"last_name":"Huc","full_name":"Huc, Ivan","first_name":"Ivan"},{"full_name":"Perret, Florent","last_name":"Perret","first_name":"Florent"},{"first_name":"Laurent","last_name":"Vial","full_name":"Vial, Laurent"},{"first_name":"Julien","last_name":"Leclaire","full_name":"Leclaire, Julien"}],"citation":{"apa":"Zhang, Y., Ourri, B., Skowron, P.-T., Jeamet, E., Chetot, T., Duchamp, C., … Leclaire, J. (2023). Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions. <i>Chemical Science</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d3sc01235b\">https://doi.org/10.1039/d3sc01235b</a>","ieee":"Y. Zhang <i>et al.</i>, “Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions,” <i>Chemical Science</i>, vol. 14, no. 26. Royal Society of Chemistry, pp. 7126–7135, 2023.","mla":"Zhang, Yuan, et al. “Self-Assembly of Achiral Building Blocks into Chiral Cyclophanes Using Non-Directional Interactions.” <i>Chemical Science</i>, vol. 14, no. 26, Royal Society of Chemistry, 2023, pp. 7126–35, doi:<a href=\"https://doi.org/10.1039/d3sc01235b\">10.1039/d3sc01235b</a>.","ama":"Zhang Y, Ourri B, Skowron P-T, et al. Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions. <i>Chemical Science</i>. 2023;14(26):7126-7135. doi:<a href=\"https://doi.org/10.1039/d3sc01235b\">10.1039/d3sc01235b</a>","chicago":"Zhang, Yuan, Benjamin Ourri, Pierre-Thomas Skowron, Emeric Jeamet, Titouan Chetot, Christian Duchamp, Ana M. Belenguer, et al. “Self-Assembly of Achiral Building Blocks into Chiral Cyclophanes Using Non-Directional Interactions.” <i>Chemical Science</i>. Royal Society of Chemistry, 2023. <a href=\"https://doi.org/10.1039/d3sc01235b\">https://doi.org/10.1039/d3sc01235b</a>.","short":"Y. Zhang, B. Ourri, P.-T. Skowron, E. Jeamet, T. Chetot, C. Duchamp, A.M. Belenguer, N. Vanthuyne, O. Cala, E. Dumont, P.K. Mandal, I. Huc, F. Perret, L. Vial, J. Leclaire, Chemical Science 14 (2023) 7126–7135.","ista":"Zhang Y, Ourri B, Skowron P-T, Jeamet E, Chetot T, Duchamp C, Belenguer AM, Vanthuyne N, Cala O, Dumont E, Mandal PK, Huc I, Perret F, Vial L, Leclaire J. 2023. Self-assembly of achiral building blocks into chiral cyclophanes using non-directional interactions. Chemical Science. 14(26), 7126–7135."},"OA_type":"gold","year":"2023","date_published":"2023-05-24T00:00:00Z","pmid":1}]