{"OA_type":"closed access","abstract":[{"text":"The decanucleotide sequence d(CCGGTACCGG) crystallizes as a four-way junction at low cobalt ion concentrations (i.e., 1 mM). When the cobalt concentration in the crystallization solution is increased to 5 mM, the sequence crystallizes as resolved B-DNA duplexes. Gel retardation studies of the decamer show both a faint slow-moving band and a much thicker fast-moving band at low cobalt ion concentrations, and only the intense fast-moving band at higher ion concentration. Circular dichroism (CD) spectroscopy of the decamer indicates a structural transition as the cobalt ion concentration in the solution is increased, probably from B-type to A-type DNA. These studies revealed that the oligomer sequence has several conformations and structures accessible to it, in a manner dependent on sequence, ion concentration, and DNA concentration.","lang":"eng"}],"status":"public","date_published":"2012-03-01T00:00:00Z","quality_controlled":"1","month":"03","title":"Crystallographic and spectroscopic studies of d(CCGGTACCGG)","language":[{"iso":"eng"}],"_id":"21151","page":"184-196","citation":{"mla":"Venkadesh, S., et al. “Crystallographic and Spectroscopic Studies of d(CCGGTACCGG).” <i>Nucleosides, Nucleotides and Nucleic Acids</i>, vol. 31, no. 3, Informa UK Limited, 2012, pp. 184–96, doi:<a href=\"https://doi.org/10.1080/15257770.2011.648363\">10.1080/15257770.2011.648363</a>.","ama":"Venkadesh S, Mandal PK, Gautham N. Crystallographic and spectroscopic studies of d(CCGGTACCGG). <i>Nucleosides, Nucleotides and Nucleic Acids</i>. 2012;31(3):184-196. doi:<a href=\"https://doi.org/10.1080/15257770.2011.648363\">10.1080/15257770.2011.648363</a>","short":"S. Venkadesh, P.K. Mandal, N. Gautham, Nucleosides, Nucleotides and Nucleic Acids 31 (2012) 184–196.","chicago":"Venkadesh, S., Pradeep K Mandal, and N. Gautham. “Crystallographic and Spectroscopic Studies of d(CCGGTACCGG).” <i>Nucleosides, Nucleotides and Nucleic Acids</i>. Informa UK Limited, 2012. <a href=\"https://doi.org/10.1080/15257770.2011.648363\">https://doi.org/10.1080/15257770.2011.648363</a>.","apa":"Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2012). Crystallographic and spectroscopic studies of d(CCGGTACCGG). <i>Nucleosides, Nucleotides and Nucleic Acids</i>. Informa UK Limited. <a href=\"https://doi.org/10.1080/15257770.2011.648363\">https://doi.org/10.1080/15257770.2011.648363</a>","ista":"Venkadesh S, Mandal PK, Gautham N. 2012. Crystallographic and spectroscopic studies of d(CCGGTACCGG). Nucleosides, Nucleotides and Nucleic Acids. 31(3), 184–196.","ieee":"S. Venkadesh, P. K. Mandal, and N. Gautham, “Crystallographic and spectroscopic studies of d(CCGGTACCGG),” <i>Nucleosides, Nucleotides and Nucleic Acids</i>, vol. 31, no. 3. Informa UK Limited, pp. 184–196, 2012."},"issue":"3","pmid":1,"external_id":{"pmid":["22356234"]},"oa_version":"None","publisher":"Informa UK Limited","year":"2012","has_accepted_license":"1","article_processing_charge":"No","publication":"Nucleosides, Nucleotides and Nucleic Acids","type":"journal_article","doi":"10.1080/15257770.2011.648363","author":[{"full_name":"Venkadesh, S.","last_name":"Venkadesh","first_name":"S."},{"full_name":"Mandal, Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","orcid":"0000-0001-5996-956X","first_name":"Pradeep K","last_name":"Mandal"},{"full_name":"Gautham, N.","first_name":"N.","last_name":"Gautham"}],"extern":"1","day":"01","intvolume":"        31","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1532-2335"],"issn":["1525-7770"]},"publication_status":"published","article_type":"original","volume":31,"date_updated":"2026-02-20T08:17:42Z","date_created":"2026-02-06T12:10:42Z"}