---
res:
  bibo_abstract:
  - The condensation of charged polymers is an important driver for the formation
    of biomolecular condensates. Recent experiments suggest that this mechanism also
    controls the clustering of eukaryotic chromosomes during the late stages of cell
    division. In this process, interchromosome attraction is driven by the condensation
    of cytoplasmic RNA and Ki-67, a charged intrinsically disordered protein that
    coats the chromosomes as a brush. Attraction between chromosomes has been shown
    to be specifically promoted by a localized charged patch on Ki-67, although the
    physical mechanism remains unclear. To elucidate this process, we combine coarse-grained
    simulations and analytical theory to study the RNA-mediated interaction between
    charged polymer brushes on the chromosome surfaces. We show that the charged patch
    on Ki-67 leads to interchromosome attraction via RNA bridging between the two
    brushes, whereby the RNA preferentially interacts with the charged patches, leading
    to stable, long-range forces. By contrast, if the brush is uniformly charged,
    bridging is basically absent due to complete adsorption of RNA onto the brush.
    Moreover, the RNA dynamics becomes caged in presence of the charged patch while
    remaining diffusive with uniform charge. Our work sheds light on the physical
    origin of chromosome clustering, while also suggesting a general mechanism for
    cells to tune work production by biomolecular condensates via different charge
    distributions.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Valerio
      foaf_name: Sorichetti, Valerio
      foaf_surname: Sorichetti
      foaf_workInfoHomepage: http://www.librecat.org/personId=ef8a92cb-c7b6-11ec-8bea-e1fd5847bc5b
    orcid: 0000-0002-9645-6576
  - foaf_Person:
      foaf_givenName: Paul
      foaf_name: Robin, Paul
      foaf_surname: Robin
      foaf_workInfoHomepage: http://www.librecat.org/personId=48c58128-57b0-11ee-9095-dc28fd97fc1d
    orcid: 0000-0002-5728-9189
  - foaf_Person:
      foaf_givenName: Ivan
      foaf_name: Palaia, Ivan
      foaf_surname: Palaia
      foaf_workInfoHomepage: http://www.librecat.org/personId=9c805cd2-4b75-11ec-a374-db6dd0ed57fa
    orcid: ' 0000-0002-8843-9485 '
  - foaf_Person:
      foaf_givenName: Alberto
      foaf_name: Hernandez-Armendariz, Alberto
      foaf_surname: Hernandez-Armendariz
  - foaf_Person:
      foaf_givenName: Sara
      foaf_name: Cuylen-Haering, Sara
      foaf_surname: Cuylen-Haering
  - foaf_Person:
      foaf_givenName: Anđela
      foaf_name: Šarić, Anđela
      foaf_surname: Šarić
      foaf_workInfoHomepage: http://www.librecat.org/personId=bf63d406-f056-11eb-b41d-f263a6566d8b
    orcid: 0000-0002-7854-2139
  bibo_doi: 10.1103/41fd-r847
  bibo_issue: '3'
  bibo_volume: 3
  dct_date: 2025^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2835-8279
  dct_language: eng
  dct_publisher: American Physical Society@
  dct_title: Charge distribution of the coating brush drives interchromosome attraction@
...