---
res:
  bibo_abstract:
  - 'Developmental patterning comprises processes that range from purely instructed,
    where external signals specify cell fates, to fully self-organized, where spatial
    patterns emerge autonomously through cellular interactions. We propose that both
    extremes—as well as the continuum of intermediate cases—can be conceptualized
    as information-processing systems, whose operation can be described using “Marr''s
    three levels of analysis”: the computational problem being solved, the algorithms
    employed, and their molecular implementation. At the first level, we argue that
    normative theories, such as information-theoretic optimization principles, provide
    a formalization of the computational problem. At the second level, we show how
    simplified information-processing architectures provide a framework for developmental
    algorithms, which are formalized mathematically using dynamical systems theory.
    At the third level, the implementation of developmental algorithms is described
    by mechanistic biophysical and gene regulatory network models.@eng'
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: David
      foaf_name: Brückner, David
      foaf_surname: Brückner
      foaf_workInfoHomepage: http://www.librecat.org/personId=e1e86031-6537-11eb-953a-f7ab92be508d
    orcid: 0000-0001-7205-2975
  - foaf_Person:
      foaf_givenName: Gašper
      foaf_name: Tkačik, Gašper
      foaf_surname: Tkačik
      foaf_workInfoHomepage: http://www.librecat.org/personId=3D494DCA-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-6699-1455
  bibo_doi: 10.1103/fdcf-dkws
  bibo_volume: 4
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2835-8279
  dct_language: eng
  dct_publisher: American Physical Society@
  dct_title: 'Marr''s three levels for embryonic development: Information, dynamical
    systems, gene networks@'
...