---
res:
  bibo_abstract:
  - The advantageous characteristics attributed to the 19F nucleus have made it a
    popular target for NMR once again in recent years. Aside from solution NMR, an
    increasing number of studies have been conducted applying solid-state magic-angle-spinning
    NMR to fluorine-labeled samples. Here, the high chemical shift anisotropy and
    strong dipolar couplings can be utilized to get structural insights into proteins
    and measure long distances. Despite increasing popularity and promising benefits,
    the sensitivity of biomolecular 19F MAS NMR often suffers from slow longitudinal
    T1 relaxation and therefore long recycle delays. In this work, we expand paramagnetic
    doping, an approach commonly used to reduce proton T1 relaxation times, to 19F-labeled
    biological samples. We study the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F and
    13C T1 and T2 relaxation in a [5-19F13C]-tryptophan-labeled protein via 19F-detected
    MAS NMR experiments. The observed paramagnetic relaxation enhancement substantially
    reduces measurement times of 19F MAS NMR experiments without compromising resolution.
    Additionally, we report the chemical-shift assignments of all four fluorotryptophan
    signals in the 12 × 39 kDa large protein using a mutagenesis approach.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Lea Marie
      foaf_name: Becker, Lea Marie
      foaf_surname: Becker
      foaf_workInfoHomepage: http://www.librecat.org/personId=36336939-eb97-11eb-a6c2-c83f1214ca79
    orcid: 0000-0002-6401-5151
  - foaf_Person:
      foaf_givenName: Paul
      foaf_name: Schanda, Paul
      foaf_surname: Schanda
      foaf_workInfoHomepage: http://www.librecat.org/personId=7B541462-FAF6-11E9-A490-E8DFE5697425
    orcid: 0000-0002-9350-7606
  bibo_doi: 10.15479/AT-ISTA-21284
  dct_date: 2026^xs_gYear
  dct_publisher: Institute of Science and Technology Austria@
  dct_title: Research data for "Accelerated 19F biomolecular magic-angle spinning
    NMR with paramagnetic dopants"@
...