---
res:
  bibo_abstract:
  - An individual's phenotype reflects a complex interplay of the direct effects of
    their DNA, epigenetic modifications of their DNA induced by their parents, and
    indirect effects of their parents' DNA. Here, we derive how the genetic variance
    within a population is changed under the influence of indirect maternal, paternal
    and parent-of-origin effects under random mating. We also consider indirect effects
    of a sibling, in particular how the genetic variance is altered when looking at
    the phenotypic difference between two siblings. The calculations are then extended
    to include assortative mating (AM), which alters the variance by inducing increased
    homozygosity and correlations within and across loci. AM likely leads to covariance
    of parental genetic effects, a measure of the similarity of parents in the indirect
    effects they have on their children. We propose that this assortment for parental
    characteristics, where biological parents create similar environments for their
    children, can create shared parental effects across traits and the appearance
    of cross-trait AM. Our theory shows how the resemblance among relatives increases
    under both AM, indirect and parent-of-origin effects. When our model is used to
    predict correlations among relatives in human height, we find that explaining
    the patterns observed in real data requires both indirect genetic effects and
    assortative mating. The degree to which direct, indirect and epigenetic effects
    shape the phenotypic variance of complex traits remains an open question that
    requires large-scale family data to be resolved.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Ilse
      foaf_name: Krätschmer, Ilse
      foaf_surname: Krätschmer
      foaf_workInfoHomepage: http://www.librecat.org/personId=30d4014e-7753-11eb-b44b-db6d61112e73
    orcid: 0000-0002-5636-9259
  - foaf_Person:
      foaf_givenName: Matthew Richard
      foaf_name: Robinson, Matthew Richard
      foaf_surname: Robinson
      foaf_workInfoHomepage: http://www.librecat.org/personId=E5D42276-F5DA-11E9-8E24-6303E6697425
    orcid: 0000-0001-8982-8813
  bibo_doi: 10.1093/genetics/iyag042
  bibo_issue: '4'
  bibo_volume: 232
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1943-2631
  dct_language: eng
  dct_publisher: Oxford University Press@
  dct_title: A quantitative genetic model for indirect genetic effects and genomic
    imprinting under random and assortative mating@
  fabio_hasPubmedId: '41677404'
...