---
res:
  bibo_abstract:
  - Cells are defined by lipid membranes that differ in their structure across the
    tree of life. While the membranes of most bacteria and eukaryotes consist of single-headed
    bilayer lipids, the membranes of archaea are composed of mixtures of single-headed
    bilayer lipids and double-headed bolalipids. Archaeal bolalipids can adopt straight
    or u-shaped conformations, enabling them—together with bilayer lipids—to control
    whether membranes form bilayer or monolayer structures. Yet, the physical principles
    governing archaeal membranes remain largely unexplored, especially how membrane
    structure couples to externally imposed curvature during membrane remodeling.
    Here, we perform coarse-grained molecular dynamics simulations of toroidal vesicles
    to systematically probe the effects of all relevant combinations of mean and Gaussian
    curvatures on shape stability and lipid organization. We find that soft bilayer
    membranes can sustain all curvatures induced, whereas rigid bolalipid monolayer
    membranes either transition to different vesicle shapes or rupture. Bilayer-mimicking
    u-shaped bolalipids and bilayer lipids are spatially accumulated in regions of
    high mean membrane curvature independent of Gaussian curvature. Our work identifies
    curvature–composition coupling as a physical signature of archaeal membrane remodeling.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Felix F
      foaf_name: Frey, Felix F
      foaf_surname: Frey
      foaf_workInfoHomepage: http://www.librecat.org/personId=a0270b37-8f1a-11ec-95c7-8e710c59a4f3
    orcid: 0000-0001-8501-6017
  - foaf_Person:
      foaf_givenName: Miguel
      foaf_name: Santana de Freitas Amaral, Miguel
      foaf_surname: Santana de Freitas Amaral
      foaf_workInfoHomepage: http://www.librecat.org/personId=4f2d02dd-47a9-11ec-ad10-82820ed3f501
  - foaf_Person:
      foaf_givenName: Anđela
      foaf_name: Šarić, Anđela
      foaf_surname: Šarić
      foaf_workInfoHomepage: http://www.librecat.org/personId=bf63d406-f056-11eb-b41d-f263a6566d8b
    orcid: 0000-0002-7854-2139
  bibo_doi: 10.1063/5.0325170
  bibo_issue: '14'
  bibo_volume: 164
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/ 0021-9606
  - http://id.crossref.org/issn/1089-7690
  dct_language: eng
  dct_publisher: AIP Publishing@
  dct_title: 'Cracking donuts and sorting lipids: Geometry controls archaeal membrane
    stability and lipid organization@'
...
