---
res:
  bibo_abstract:
  - The mammalian brain organises knowledge about entities in the world and relationships
    between them using cognitive maps. When forming a cognitive map, there is a necessary
    trade-off between extending the map to make novel inferences, and storing a veridical
    copy of past experience. However, the neural mechanisms that control this trade-off
    remain unknown. Using a cross-scale approach that combines a pharmacological intervention
    in humans with neural network modelling, we show that the neuromodulator noradrenaline
    elicits a significant ‘spread of association’ across hippocampal cognitive maps.
    This neural spread of association can be explained by changes in synaptic plasticity
    that predict overgeneralisation in behaviour. Thus, elevated noradrenaline during
    learning increases the ‘smoothing kernel’ for plasticity across the cognitive
    map, allowing disparate memories to become linked and distorted.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Renée S.
      foaf_name: Koolschijn, Renée S.
      foaf_surname: Koolschijn
  - foaf_Person:
      foaf_givenName: Prakriti
      foaf_name: Parthasarathy, Prakriti
      foaf_surname: Parthasarathy
  - foaf_Person:
      foaf_givenName: Michael
      foaf_name: Browning, Michael
      foaf_surname: Browning
  - foaf_Person:
      foaf_givenName: Xenia
      foaf_name: Przygodda, Xenia
      foaf_surname: Przygodda
  - foaf_Person:
      foaf_givenName: Liliana P.
      foaf_name: Capitão, Liliana P.
      foaf_surname: Capitão
  - foaf_Person:
      foaf_givenName: William T.
      foaf_name: Clarke, William T.
      foaf_surname: Clarke
  - foaf_Person:
      foaf_givenName: Tim P
      foaf_name: Vogels, Tim P
      foaf_surname: Vogels
      foaf_workInfoHomepage: http://www.librecat.org/personId=CB6FF8D2-008F-11EA-8E08-2637E6697425
    orcid: 0000-0003-3295-6181
  - foaf_Person:
      foaf_givenName: Jill X.
      foaf_name: O’Reilly, Jill X.
      foaf_surname: O’Reilly
  - foaf_Person:
      foaf_givenName: Helen C.
      foaf_name: Barron, Helen C.
      foaf_surname: Barron
  bibo_doi: 10.1038/s41467-026-70659-x
  bibo_volume: 17
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2041-1723
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: Noradrenaline causes a spread of association in the hippocampal cognitive
    map@
  fabio_hasPubmedId: '41832186'
...