[{"supervisor":[{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","first_name":"Nicholas H","last_name":"Barton","orcid":"0000-0002-8548-5240"},{"last_name":"Maas","orcid":"0000-0002-0845-1338","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","first_name":"Jan","full_name":"Maas, Jan"}],"date_created":"2026-05-27T06:26:08Z","day":"07","file_date_updated":"2026-06-11T12:14:53Z","language":[{"iso":"eng"}],"related_material":{"record":[{"status":"public","id":"11447","relation":"part_of_dissertation"},{"id":"12513","relation":"part_of_dissertation","status":"deleted"},{"status":"public","id":"21967","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"21968"}]},"title":"How epistasis and purifying selection shape genetic diversity","ddc":["576"],"citation":{"ama":"Khudiakova K. How epistasis and purifying selection shape genetic diversity. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21918\">10.15479/AT-ISTA-21918</a>","apa":"Khudiakova, K. (2026). <i>How epistasis and purifying selection shape genetic diversity</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21918\">https://doi.org/10.15479/AT-ISTA-21918</a>","ieee":"K. Khudiakova, “How epistasis and purifying selection shape genetic diversity,” Institute of Science and Technology Austria, 2026.","mla":"Khudiakova, Kseniia. <i>How Epistasis and Purifying Selection Shape Genetic Diversity</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21918\">10.15479/AT-ISTA-21918</a>.","short":"K. Khudiakova, How Epistasis and Purifying Selection Shape Genetic Diversity, Institute of Science and Technology Austria, 2026.","chicago":"Khudiakova, Kseniia. “How Epistasis and Purifying Selection Shape Genetic Diversity.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21918\">https://doi.org/10.15479/AT-ISTA-21918</a>.","ista":"Khudiakova K. 2026. How epistasis and purifying selection shape genetic diversity. Institute of Science and Technology Austria."},"acknowledgement":"At different stages of my PhD, my work was supported by several grants: the\r\nDOC fellowship of the Austrian Academy of Sciences (26293, awarded to me),\r\nthe FWF-SFB grant (PT1032F06504 n. F65, awarded to Jan Maas), and the ERC\r\ngrant (PR1032ERC01 n. 716117, awarded to Jan Maas). I also appreciate the help\r\nfrom the Scientific Computing unit for their advice on the cluster usage.","type":"dissertation","project":[{"_id":"256E75B8-B435-11E9-9278-68D0E5697425","grant_number":"716117","call_identifier":"H2020","name":"Optimal Transport and Stochastic Dynamics"},{"grant_number":"26293","name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8"},{"_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","grant_number":"F6504","name":"Taming Complexity in Partial Differential Systems"}],"_id":"21918","doi":"10.15479/AT-ISTA-21918","page":"89","author":[{"full_name":"Khudiakova, Kseniia","first_name":"Kseniia","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","orcid":"0000-0002-6246-1465","last_name":"Khudiakova"}],"ec_funded":1,"publisher":"Institute of Science and Technology Austria","acknowledged_ssus":[{"_id":"ScienComp"}],"date_updated":"2026-06-12T12:43:35Z","publication_status":"published","month":"06","date_published":"2026-06-07T00:00:00Z","department":[{"_id":"GradSch"},{"_id":"NiBa"},{"_id":"JaMa"}],"article_processing_charge":"No","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"oa_version":"Published Version","alternative_title":["ISTA Thesis"],"file":[{"relation":"source_file","file_name":"thesis.zip","date_created":"2026-06-09T08:34:38Z","file_id":"21965","creator":"kkhudiak","file_size":20549813,"checksum":"0cff64ae74f0f9f2d7011700c82f700a","content_type":"application/x-zip-compressed","access_level":"closed","date_updated":"2026-06-09T08:40:48Z"},{"embargo_to":"open_access","content_type":"application/pdf","checksum":"547ae42de37cc86894af283f1664dbc8","access_level":"closed","file_size":9387029,"creator":"kkhudiak","date_updated":"2026-06-11T12:14:53Z","relation":"main_file","embargo":"2027-06-10","date_created":"2026-06-09T12:28:51Z","file_name":"2026_Khudiakova_Ksenia_Thesis.pdf","file_id":"21969"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publication_identifier":{"issn":["2663-337X"]},"OA_place":"publisher","corr_author":"1","has_accepted_license":"1","year":"2026","status":"public","degree_awarded":"PhD"}]