---
res:
  bibo_abstract:
  - Balancing selection, a form of selection that maintains genetic diversity, is
    difficult to detect, and the importance of balancing selection for the maintenance
    of genetic variation may be larger than often assumed. We model the possibility
    that the diversity-promoting effects of balancing selection extend to other loci
    that show sign epistasis with a locus under balancing selection. Rather than focusing
    on overdominance, as was done in previous efforts, we explore the effects of negative
    frequency dependence and show that this has important effects on the conditions
    under which the diversity-promoting effect of epistasis can occur in diploids.
    Our results show that not only recombination rate but also the dominance of sign
    epistasis are key parameters that determine the maintenance of polymorphism beyond
    the locus under direct balancing selection. We suggest that the effect we explore
    may play a significant role, especially when balancing selection acts on major
    effect loci.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Kseniia
      foaf_name: Khudiakova, Kseniia
      foaf_surname: Khudiakova
      foaf_workInfoHomepage: http://www.librecat.org/personId=4E6DC800-AE37-11E9-AC72-31CAE5697425
    orcid: 0000-0002-6246-1465
  - foaf_Person:
      foaf_givenName: Nicholas H
      foaf_name: Barton, Nicholas H
      foaf_surname: Barton
      foaf_workInfoHomepage: http://www.librecat.org/personId=4880FE40-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8548-5240
  - foaf_Person:
      foaf_givenName: Goran
      foaf_name: Arnqvist, Goran
      foaf_surname: Arnqvist
  bibo_doi: 10.1101/2025.04.09.647826
  dct_date: 2026^xs_gYear
  dct_language: eng
  dct_title: Sign epistasis extends the effects of balancing selection on genetic
    diversity@
...