article published yes Daniel Williams-Jones author 128eaab9-b327-11f0-bdbe-e02d5abac73b Jack Peter Kelly Bravo author 96aecfa5-8931-11ee-af30-aa6a5d6eee0e0000-0003-0456-0753 JaBr department In this issue of Cell Host & Microbe, Osterman et al. discover aRES,1 a new family of bacterial immune proteins that deplete cellular NAD+, generating cleavage products that cannot be utilized by canonical phage NAD+ regeneration pathways. They identify the invader-specific trigger for aRES and characterize two distinct evolutionary countermeasures employed by phages to resist aRES. Elsevier2026 eng 1931-3128 1934-6069 4226958410.1016/j.chom.2026.05.013 346978-980 Williams-Jones D, Bravo JPK. 2026. NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back. Cell Host &#38; Microbe. 34(6), 978–980. D. Williams-Jones, J.P.K. Bravo, Cell Host &#38; Microbe 34 (2026) 978–980. Williams-Jones, Daniel, and Jack Peter Kelly Bravo. “NAD to the Bone: How Bacteria Put Phages under ARES-t … and How Phages Fight Back.” <i>Cell Host &#38; Microbe</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.chom.2026.05.013">https://doi.org/10.1016/j.chom.2026.05.013</a>. Williams-Jones, D., &#38; Bravo, J. P. K. (2026). NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back. <i>Cell Host &#38; Microbe</i>. Elsevier. <a href="https://doi.org/10.1016/j.chom.2026.05.013">https://doi.org/10.1016/j.chom.2026.05.013</a> D. Williams-Jones and J. P. K. Bravo, “NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back,” <i>Cell Host &#38; Microbe</i>, vol. 34, no. 6. Elsevier, pp. 978–980, 2026. Williams-Jones, Daniel, and Jack Peter Kelly Bravo. “NAD to the Bone: How Bacteria Put Phages under ARES-t … and How Phages Fight Back.” <i>Cell Host &#38; Microbe</i>, vol. 34, no. 6, Elsevier, 2026, pp. 978–80, doi:<a href="https://doi.org/10.1016/j.chom.2026.05.013">10.1016/j.chom.2026.05.013</a>. Williams-Jones D, Bravo JPK. NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back. <i>Cell Host &#38; Microbe</i>. 2026;34(6):978-980. doi:<a href="https://doi.org/10.1016/j.chom.2026.05.013">10.1016/j.chom.2026.05.013</a> 219962026-06-14T22:01:42Z2026-06-22T07:11:28Z