---
res:
  bibo_abstract:
  - "Evolutionary biology examines how the genetic and phenotypic composition\r\nof
    populations changes over time. An important goal is to determine the\r\nfixation
    probability of a single advantageous mutant that arises in a homogeneous\r\npopulation
    of N residents. Many real populations experience environmental\r\ngradients that
    cause mutations to be beneficial in some spatial\r\nregions but harmful in others.
    Here, we study the fixation probability of a\r\nmutant placed on a simple one-dimensional
    spatial structure that experiences\r\nsuch a gradient. The mutant’s fitness varies
    linearly from1 − s to 1 + s, whereas\r\nthe resident fitness is constant and equal
    to 1. The existing literature suggests\r\nthat such heterogeneity in the mutant’s
    fitness should lead to a decrease in its\r\nfixation probability. However, in
    this work, we find that small, non-negligible\r\ngradients (s < 1=√N) substantially
    increase the fixation probability,while larger\r\ngradients (s > (log N)/√N) substantially
    decrease it.Moreover, we quantify the\r\nstrength of this phenomenon analytically
    and we precisely delimit the range of\r\nthe gradients for which it occurs. Our
    computer simulations closely match\r\nthose findings. Altogether, our results
    indicate that subjecting a simple\r\npopulation structure to natural environmental
    conditions can produce strong\r\ncounterintuitive effects.@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Jakub
      foaf_name: Svoboda, Jakub
      foaf_surname: Svoboda
      foaf_workInfoHomepage: http://www.librecat.org/personId=130759D2-D7DD-11E9-87D2-DE0DE6697425
    orcid: 0000-0002-1419-3267
  - foaf_Person:
      foaf_givenName: Hossein
      foaf_name: Nemati, Hossein
      foaf_surname: Nemati
  - foaf_Person:
      foaf_givenName: Josef
      foaf_name: Tkadlec, Josef
      foaf_surname: Tkadlec
      foaf_workInfoHomepage: http://www.librecat.org/personId=3F24CCC8-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-1097-9684
  - foaf_Person:
      foaf_givenName: Kamran
      foaf_name: Kaveh, Kamran
      foaf_surname: Kaveh
  - foaf_Person:
      foaf_givenName: Krishnendu
      foaf_name: Chatterjee, Krishnendu
      foaf_surname: Chatterjee
      foaf_workInfoHomepage: http://www.librecat.org/personId=2E5DCA20-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-4561-241X
  bibo_doi: 10.1038/s41467-026-71777-2
  bibo_volume: 17
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2041-1723
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: The effect of the fitness gradient on fixation probability@
  fabio_hasPubmedId: '41997932'
...