{"department":[{"_id":"MiSi"}],"page":"369 - 383","acknowledgement":"J.R. was supported by a Boehringer Ingelheim Fonds PhD stipend.","citation":{"ista":"Renkawitz J, Lademann C, Jentsch S. 2014. Mechanisms and principles of homology search during recombination. Nature Reviews Molecular Cell Biology. 15(6), 369–383.","ama":"Renkawitz J, Lademann C, Jentsch S. Mechanisms and principles of homology search during recombination. <i>Nature Reviews Molecular Cell Biology</i>. 2014;15(6):369-383. doi:<a href=\"https://doi.org/10.1038/nrm3805\">10.1038/nrm3805</a>","short":"J. Renkawitz, C. Lademann, S. Jentsch, Nature Reviews Molecular Cell Biology 15 (2014) 369–383.","chicago":"Renkawitz, Jörg, Claudio Lademann, and Stefan Jentsch. “Mechanisms and Principles of Homology Search during Recombination.” <i>Nature Reviews Molecular Cell Biology</i>. Nature Publishing Group, 2014. <a href=\"https://doi.org/10.1038/nrm3805\">https://doi.org/10.1038/nrm3805</a>.","apa":"Renkawitz, J., Lademann, C., &#38; Jentsch, S. (2014). Mechanisms and principles of homology search during recombination. <i>Nature Reviews Molecular Cell Biology</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nrm3805\">https://doi.org/10.1038/nrm3805</a>","mla":"Renkawitz, Jörg, et al. “Mechanisms and Principles of Homology Search during Recombination.” <i>Nature Reviews Molecular Cell Biology</i>, vol. 15, no. 6, Nature Publishing Group, 2014, pp. 369–83, doi:<a href=\"https://doi.org/10.1038/nrm3805\">10.1038/nrm3805</a>.","ieee":"J. Renkawitz, C. Lademann, and S. Jentsch, “Mechanisms and principles of homology search during recombination,” <i>Nature Reviews Molecular Cell Biology</i>, vol. 15, no. 6. Nature Publishing Group, pp. 369–383, 2014."},"intvolume":"        15","publist_id":"4755","author":[{"first_name":"Jörg","id":"3F0587C8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2856-3369","full_name":"Renkawitz, Jörg","last_name":"Renkawitz"},{"full_name":"Lademann, Claudio","last_name":"Lademann","first_name":"Claudio"},{"last_name":"Jentsch","full_name":"Jentsch, Stefan","first_name":"Stefan"}],"doi":"10.1038/nrm3805","issue":"6","_id":"2215","publication":"Nature Reviews Molecular Cell Biology","abstract":[{"text":"Homologous recombination is crucial for genome stability and for genetic exchange. Although our knowledge of the principle steps in recombination and its machinery is well advanced, homology search, the critical step of exploring the genome for homologous sequences to enable recombination, has remained mostly enigmatic. However, recent methodological advances have provided considerable new insights into this fundamental step in recombination that can be integrated into a mechanistic model. These advances emphasize the importance of genomic proximity and nuclear organization for homology search and the critical role of homology search mediators in this process. They also aid our understanding of how homology search might lead to unwanted and potentially disease-promoting recombination events.","lang":"eng"}],"scopus_import":1,"quality_controlled":"1","date_updated":"2021-01-12T06:56:03Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_published":"2014-05-14T00:00:00Z","oa_version":"None","date_created":"2018-12-11T11:56:22Z","language":[{"iso":"eng"}],"month":"05","day":"14","volume":15,"publisher":"Nature Publishing Group","type":"journal_article","year":"2014","title":"Mechanisms and principles of homology search during recombination","publication_status":"published","status":"public"}