{"doi":"10.1021/jacsau.1c00443","publisher":"American Chemical Society","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"22207","quality_controlled":"1","day":"10","publication_status":"published","extern":"1","date_updated":"2026-07-15T05:55:35Z","page":"66-73","date_created":"2026-06-30T06:30:18Z","pmid":1,"oa_version":"Published Version","intvolume":"         2","has_accepted_license":"1","scopus_import":"1","DOAJ_listed":"1","issue":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1021/jacsau.1c00443"}],"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"publication_identifier":{"eissn":["2691-3704"]},"year":"2021","article_processing_charge":"No","abstract":[{"text":"Phase separation is a ubiquitous process and finds applications in a variety of biological, organic, and inorganic systems. Nature has evolved the ability to control phase separation to both regulate cellular processes and make composite materials with outstanding mechanical and optical properties. Striking examples of the latter are the vibrant blue and green feathers of many bird species, which are thought to result from an exquisite control of the size and spatial correlations of their phase-separated microstructures. By contrast, it is much harder for material scientists to arrest and control phase separation in synthetic materials with such a high level of precision at these length scales. In this Perspective, we briefly review some established methods to control liquid–liquid phase separation processes and then highlight the emergence of a promising arrest method based on phase separation in an elastic polymer network. Finally, we discuss upcoming challenges and opportunities for fabricating microstructured materials via mechanically controlled phase separation.","lang":"eng"}],"volume":2,"language":[{"iso":"eng"}],"external_id":{"pmid":["35098222"]},"date_published":"2021-12-10T00:00:00Z","article_type":"original","oa":1,"publication":"JACS Au","status":"public","author":[{"first_name":"Carla","last_name":"Fernández-Rico","full_name":"Fernández-Rico, Carla","id":"492def71-6250-11f0-b278-d41dbd241b62"},{"last_name":"Sai","first_name":"Tianqi","full_name":"Sai, Tianqi"},{"last_name":"Sicher","first_name":"Alba","full_name":"Sicher, Alba"},{"last_name":"Style","first_name":"Robert W.","full_name":"Style, Robert W."},{"last_name":"Dufresne","first_name":"Eric R.","full_name":"Dufresne, Eric R."}],"type":"journal_article","title":"Putting the squeeze on phase separation","OA_place":"publisher","ddc":["540"],"month":"12","keyword":["phase separation","arrest","bird feathers","elasticity","polymer networks","microstructured materials"],"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","citation":{"ama":"Fernández-Rico C, Sai T, Sicher A, Style RW, Dufresne ER. Putting the squeeze on phase separation. <i>JACS Au</i>. 2021;2(1):66-73. doi:<a href=\"https://doi.org/10.1021/jacsau.1c00443\">10.1021/jacsau.1c00443</a>","short":"C. Fernández-Rico, T. Sai, A. Sicher, R.W. Style, E.R. Dufresne, JACS Au 2 (2021) 66–73.","ieee":"C. Fernández-Rico, T. Sai, A. Sicher, R. W. Style, and E. R. Dufresne, “Putting the squeeze on phase separation,” <i>JACS Au</i>, vol. 2, no. 1. American Chemical Society, pp. 66–73, 2021.","mla":"Fernández-Rico, Carla, et al. “Putting the Squeeze on Phase Separation.” <i>JACS Au</i>, vol. 2, no. 1, American Chemical Society, 2021, pp. 66–73, doi:<a href=\"https://doi.org/10.1021/jacsau.1c00443\">10.1021/jacsau.1c00443</a>.","chicago":"Fernández-Rico, Carla, Tianqi Sai, Alba Sicher, Robert W. Style, and Eric R. Dufresne. “Putting the Squeeze on Phase Separation.” <i>JACS Au</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/jacsau.1c00443\">https://doi.org/10.1021/jacsau.1c00443</a>.","apa":"Fernández-Rico, C., Sai, T., Sicher, A., Style, R. W., &#38; Dufresne, E. R. (2021). Putting the squeeze on phase separation. <i>JACS Au</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacsau.1c00443\">https://doi.org/10.1021/jacsau.1c00443</a>","ista":"Fernández-Rico C, Sai T, Sicher A, Style RW, Dufresne ER. 2021. Putting the squeeze on phase separation. JACS Au. 2(1), 66–73."},"OA_type":"gold"}